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sleep-apnea-syndromes Clinical Trials

A listing of sleep-apnea-syndromes medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 333 clinical trials
S Santos, MD

Assessment of OSA in Latin American and Response to Neuromod Therapy

The purpose of this study is to characterize the upper airway of Latin American subjects who have been diagnosed with moderate/severe obstructive sleep apnea (OSA) and assess response to a neuromodulation therapy to treat OSA.

18 years of age All Phase N/A
H Howard S Gordon, MD BS

DRonabinol Treatment of OSA

This is an open-label trial that tests the effectiveness of Dronabinol in treating obstructive sleep apnea (OSA). All participants will take oral Dronabinol for two weeks. Sleep studies will be conducted before and after treatment to measure OSA severity.

- 65 years of age All Phase 1/2
N Ning Ding, doctor

XOR Levels in OSA Patients (XOR-OSA)

The level of xanthine oxidoreductase (XOR) in plasma is associated with oxidative stress and inflammation. Obstructive Sleep Apnea (OSA) is characterized by repeated upper airway obstruction and apneas during sleep, leading to chronic intermittent hypoxemia. The specific role of XOR in OSA, its relationship with the severity of OSA, and …

18 - 80 years of age All Phase N/A
J Jenny Mitchell

Hypoglossal Nerve Stimulation for the Treatment of Adult Obstructive Sleep Apnea

The goal of this interventional study is to assess the safety and performance of the XII Medical Hypoglossal Nerve Stimulation (HGNS) System in people who have moderate to severe Obstructive Sleep Apnea (OSA). Participation in this study involves being implanted with a Neurostimulator which provides electrical stimulation of the hypoglossal …

21 years of age All Phase N/A

Boosting CPAP Use in Adults With Severe Sleep Apnea: Role of Motivation and Psychological Factors

The goal of this randomized prospective clinical trial is to examine whether phenotypic traits, psychological characteristics, assessed by STAI (engl. The State-Trait Anxiety Inventory) and IPIP50S (engl. International Personality Item Pool) questionnaires, and patients' self-efficacy, assessed by SEMSA (engl. Self-Eficacy Measure for Sleep Apnea) questionnaire, are associated with CPAP adherence …

18 years of age All Phase N/A
S Sara Kukuljan, BS, RN

Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Mandibular Advancement

The purpose of this study is to evaluate the effectiveness, feasibility, and safety of mandibular advancement devices (MAD) for treating severe obstructive sleep apnea (OSA) in patients who are CPAP intolerant and have failed hypoglossal nerve stimulation (HGNS).

18 - 70 years of age All Phase N/A
N Nicole Calianese, BS

Trazodone on OSA Endotypes

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for spontaneous upper airway (UA) dilator muscle recruitment. As a consequence they are exposed to …

21 - 70 years of age All Phase 1/2
B Betty Monari

App-Based Optimization of Long-Term CPAP Adherence and Quality of Life

The purpose of this study is to optimize the time of CPAP usage to at least 6 hours a night for 6 nights per week for people who have OSA with the help of a smartphone application called SmartWell24. This application aims to target CPAP adherence.

18 years of age All Phase N/A
a ahmed elfahl, lecturer

Efficacy of Shitali Respiratory Rehabilitation Program in Obstructive Sleep Apnea

obstructive sleep apnea has a negative impact on blood pressure of patients, sleeping quality, and respiration

35 - 55 years of age All Phase N/A
M Mohamed Faisal Abdul Hamid

Conventional CPAP Airsense 10 VS Portable Air-Mini CPAP For Obstructive Sleep Apnea (CASPAM)

Obstructive sleep apnea (OSA) has been one of the topmost global health problems. It is an underdiagnosed disease which have a huge burden on healthcare if left untreated. Almost 80-90% of adults are underdiagnosed of OSA Obesity primarily is one of the supreme risk factors for developing OSA. Globally, obesity …

18 years of age All Phase N/A

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