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sleep-apnea-syndromes Clinical Trials

A listing of sleep-apnea-syndromes medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 326 clinical trials
C Cheng Zhang, PhD

Evaluating the Diagnostic Efficacy of Smartwatch and Smartphone for Sleep Apnea

The purpose of this study is to evaluate the diagnostic value of smartphones and watches for OSA screening. The study will be conducted in individuals suspected of having OSA. Subjects will undergo "gold standard" PSG assessment (overnight polysomnography with staff supervision) in a sleep monitoring room, while wearing a smartwatch …

18 years of age All Phase N/A
T Tony Sehr, MD

Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients

The goal of this observational study is to investigate biomarkers and neurocognitive markers of neurodegenerative processes in obstructive sleep apnea patients. The main questions the study aims to answer are: Does neurodegeneration assessed by neurobiological markers and neurocognitive test performance exists in obstructive sleep apnea? Are these neurodegenerative markers are …

18 years of age All Phase N/A
M Marie Joyeux-Faure, PharmD, PhDm

Long-term Follow-up in Patients Included in the European Sleep Apnea Data Base (ESADA)

The European database ESADA, containing data from more than 30,000 patients with very different severities of obstructive sleep apnea (OSA) syndrome, prospectively collects data from patients referred to academic sleep laboratories in many European countries (https://esada.med.gu.se/). Since 2007, Grenoble is one of the two French centers with Paris and is …

18 - 80 years of age All Phase N/A
K Karma Lhamo, MS

Reliability of the Samsung Galaxy for the Detection of Moderate to Severe Obstructive Sleep Apnea

The study will test the reliability of the Samsung Galaxy for the Detection of Moderate to Severe Obstructive Sleep Apnea (OSA)

22 years of age All Phase N/A
J Jesus Gomez Sanchez, Dr

Clinical Evaluation of a Paediatric Sleep Diagnosis Technology

The objective of this project is to gather research data and subsequently evaluate algorithms to demonstrate clinical efficacy of a novel sleep apnoea detection system in the paediatric population. The Study will involve patients who will have been referred for diagnosis of sleep apnoea, and the ultimate aim will be …

1 - 18 years of age All Phase N/A
A Amar Shah

AcuPebble to Remotely Monitor Patients With OSA on CPAP Therapy

Obstructive sleep apnoea (OSA) is a breathing problem that happens when you sleep. It is treated by a machine called continuous positive airway pressure (CPAP) therapy. The goal of this observational trial is to test how well a new wearable device can detect ongoing OSA in patients undergoing treatment with …

18 - 80 years of age All Phase N/A
M Mads HS Moxness, md phd

Virtual Surgery of the Upper Airways

Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by repetitive collapses of the upper airways resulting in impaired breathing, oxygen desaturation and sleep disturbances. OSA has a massive impact on global health contributing directly to cardiovascular diseases, insulin resistance, metabolic syndrome and daytime fatigue and is repeatedly …

18 - 70 years of age All Phase N/A
K Kevin M Motz, MD

Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics

Obstructive sleep apnea (OSA) is a highly prevalent disease resulting from dynamic upper airway collapse during sleep. Continuous positive airway pressure (CPAP) is highly efficacious but high rates of non-adherence to CPAP leaves large number of OSA patients at risk for cardiometabolic sequelae. Inspire™ is an FDA-approved hypoglossal nerve stimulation …

18 years of age All Phase N/A
J Jing Xu, M.D

Relationship Between Vascular Endothelial Dysfunction and Beat-to-beat Blood Pressure Variability in Patients With OSAS

It is thought that intermittent hypoxia, poor tissue oxygenation, and perfusion in OSA can lead to eNOS uncoupling. Uncoupled eNOS can reduce nitric oxide (NO), which will result in an imbalance of contraction and diastole. Furthermore, OSA may increase beat-to-to BPV via the characteristic acute blood pressure peaks that follow …

18 years of age All Phase N/A
L Luigi Ferini-Strambi, Prof. MD

Multidisciplinary Network OSA Code (Obstructive Apnea Syndrome): Digital Operative Model in Public Health for an Early Diagnosis and Therapy Monitoring

Obstructive Sleep Apnea Syndrome (OSAS) is a sleep related breathing disorder with high epidemiological impact (9-38% of general population), more frequently reported in male gender and increasing with the age. Pathognomonic OSAS symptoms are snoring, excessive daytime sleepiness, sleep fragmentation, awakening during the night often for nocturia and morning headache. …

18 years of age All Phase N/A

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