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Coronary Artery Disease Clinical Trials

A listing of Coronary Artery Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 520 clinical trials
A Aju Pazhenkottil

Complementary Investigation of Perfusion and Anatomy Measures of the Heart With MRI and Combined PET/MRI

The goal of this observational study is to evaluate the complimentary information of anatomy, perfusion and viability of PET and MR. The main question[s] it aims to answer are: to compare perfusion and anatomy measurements and perfusion related signals from PET and MR imaging and estimate its prognostic values. to …

18 years of age All Phase N/A

MAIN-IMAGE Registry

All comers registry with patients with chronic coronary syndrome or acute coronary syndrome who underwent intracoronary imaging during cardiac catherization. The aim is to identify plaque characteristics on OCT or IVUS that are associated with adverse cardiac events including myocardial infarction and atherosclerotic progression.

18 years of age All Phase N/A
J Jonica Campolo, MSc

Vascular Senescence and Atherosclerotic Plaque Vulnerability

Chronological aging significantly contributes to structural and functional alterations in the vasculature, making it a major risk factor for atherosclerotic disease and its acute thrombotic events. DNA damage, including telomeric, non-telomeric, and mitochondrial damage, is recognized as a key initiator of vascular aging and atherogenesis. There is abundant evidence indicating …

18 - 75 years of age All Phase N/A
K Karlis Trusinskis, Prof

Latvian Early Atherosclerosis Registry

Atherosclerosis and its complications are a global problem. There are several widely known and proven risk factors that promotes atherogenesis in the majority of patients. However, significant proportion of apparently healthy and young patients with cardiovascular disease but yet without recognized atherogenesis promoting risk factors can be observed in clinical …

18 - 65 years of age All Phase N/A
M Md Zahid Hasan, MD

Clinical and Angiographic Outcomes of Post-drug-coated Balloon Angioplasty in Native Coronary Lesions

The progression of cardiac revascularization techniques, starting with standard balloon angioplasty (POBA) and progressing to the creation of drug-coated balloons (DCB) and drug-eluting stents (DES). The study's justification is presented, with a focus on the significance of comprehending the clinical and angiographic outcomes of DCB angioplasty, especially when considering the …

18 years of age All Phase N/A

Coronary Evaluation And Guided Lesion Exploration Using Photon-counting CT and Intracoronary Imaging Techniques

This study evaluates the diagnostic accuracy and limitations of photon-counting computed tomography (PCCT) in characterizing coronary plaque, with comparisons to optical coherence tomography (OCT) and intravascular ultrasound (IVUS). The objective is to assess whether cardiac ultra-high resolution (UHR) PCCT -with its improved spatial resolution and superior soft tissue contrast relative …

18 years of age All Phase N/A
C Chunjian Li, MD, PhD

A Multi-omics Study of "Healthy" Premature CAD Patients

The goal of this multi-center observational clinical trial is to investigate the genetic risk factors of patients with premature CAD and none traditional CAD risk factors through a multi-omics approach. The main questions it aims to answer are: Genetic risk factors & metabolic fingerprints of patients with premature CAD and …

18 - 75 years of age All Phase N/A
D Dr Ann Cheng

Decision Support Tool for Revascularisation Options in Coronary Artery Disease

Together with patients and healthcare professionals, we want to design a Decision Support Tool (DST) that will help people with coronary artery disease to understand and choose treatments that best reflect their preferences and values. Coronary artery disease (CAD) is a leading cause of death. Blood vessels supplying oxygen to …

years of age All Phase N/A
Z Zeynal KİZİR, PhD Student

Self-Efficacy and Medication Adherence in Patients With Coronary Artery Disease: A Descriptive Study

This descriptive study aims to examine the relationship between self-efficacy and medication adherence in individuals with coronary artery disease (CAD). The study will be conducted between March and October 2025 at Adıyaman University Training and Research Hospital with a planned sample size of 135 participants. Data will be collected using …

18 years of age All Phase N/A
M Minku Chon, MD, PhD

The Study to Evaluate the Safety and Efficacy of the Onyx Family

Observation of the safety and efficacy of 1-month dual antiplatelet therapy (DAPT) after percutaneous coronary intervention using Onyx family stents in elderly patients aged 75 years or older

75 - 100 years of age All Phase N/A

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