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occlusions Clinical Trials

A listing of occlusions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 16 clinical trials
W Wei Hu, MD

Extending the Time Window for Intravenous Tenecteplase in Patients With Distal Medium Vessel Occlusions Stroke

To assess the safety and efficacy of beyond time window TNK intravenous thrombolysis for distal Medium Vessel Occlusion (MeVO) related stroke in a prospective randomized clinical trial.

18 years of age All Phase N/A
J Jennifer Gimeno

Treatment of Calcific Total Occlusions in Peripheral Artery Disease

Prospective, multi-center, non-randomized, open label, clinical study intended to provide data to demonstrate safety and performance of the SoundBite Crossing System XS Peripheral.

19 years of age All Phase N/A

Coronary Crossing System in Patients With Coronary Chronic Total Occlusions

This is a prospective and multicenter clinical investigation aiming to evaluate the safety and effectiveness of coronary crossing system for the treatment of patients with coronary chronic total occlusions.

18 years of age All Phase N/A

VasoStar Vibrational Guidewire System to Facilitate Crossing Coronary Artery Chronic Total Occlusions

The goal of this project is to provide an improvement in wire performance to expedite crossing difficult lesions in the coronary vasculature.

18 years of age All Phase N/A

Revascularization Versus Optimal Medical Therapy of Chronic Total Coronary Occlusions on Left Ventricular Ischemia Reduction

Rationale: Randomized trials could not yet establish favourable outcomes of CTO PCI on hard endpoints such as ejection fraction or mortality, when compared to optimal medical therapy. However, patients after CTO PCI appeared to be more frequently free of angina complaints, but the aetiology behind this is not fully understood. …

18 years of age All Phase N/A
R Roberto Diletti, MD, PhD

PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions

This prospective, multicenter, non-randomized, single arm, objective performance goal (OPG) study is designed to evaluate clinical outcomes after complete revascularization by PCI and imaging guidance (OCT) in patients with multivessel coronary artery disease including left anterior descending (LAD) presenting with stable angina, or documented silent ischemia, or non-ST segment elevation …

18 - 85 years of age All Phase N/A
X Xu Wang

Effect of Evolocumab on Chronic Total Occlusions (EVOLO-CTO)

The purpose of this study is to evaluate the effect of proprotein convertase subtilisin/kexin type-9 (PCSK9) inhibitors added to regular statin therapy on target lesion failure (TLF) and arteriosclerosis progression in patients with chronic total occlusions (CTOs) undergoing successful percutaneous coronary intervention (PCI).

18 - 80 years of age All Phase 4
B Brittany Simpson

KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children with Intestinal Failure

A multi-site, randomized, 2-arm open-label trial to determine if 4% Tetrasodium (EDTA) catheter lock solution is more effective than heparin lock (standard of care) in preventing central venous catheter occlusions in children with intestinal failure (IF) on total parenteral nutrition (TPN).

4 - 18 years of age All Phase N/A
H Holger Nef, Prof., MD

The Prospective Segeberg Registry for Coronary Chronic Total Occlusions (CTO)

A Prospective Follow-up Assessment in Bad Segeberg with Patients undergoing Recanalization for Coronary Chronic Total Occlusion Lesion/s

18 - 100 years of age All Phase N/A
K Karin Broos

Chronic Total Occlusion Registry

The aim of this CTO registry is to gather data including patient demographic date, cardiac risk factors, procedural technical data and procedural success/outcome rates. Furthermore, we aim to evaluate the safety and performance of various CTO specific guidewires, devices (such as the CrossBoss/Stingray dissection re-entry device) and other recognised and …

18 years of age All Phase N/A

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