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cartilage-injuries Clinical Trials

A listing of cartilage-injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14 clinical trials
K Klaudia Marchewa

The Hyalex First-in-Human Study

The Hyalex First-in-Human Study is a prospective, multicenter, open-label, single-arm, 2-phase, first-in-human study to evaluate the safety and technical performance of the HYALEX Knee Cartilage System for replacement of loss of articular cartilage and bone of the knee femoral condyles in symptomatic patients who require surgical treatment.

21 - 65 years of age Both Phase 1

Gait Rehabilitation to Treat FastOA

The purpose of this study is to determine the effects of real-time gait biofeedback delivered over a 6-week period on early markers of FastOA and conduct 6-week and 6-month follow-up assessments in anterior cruciate ligament reconstructed patients.

16 - 35 years of age Both Phase N/A
A Asbjørn Årøen, PhD MD

Autologous Cartilage Implantation vs Arthroscopic Debridement

82 patients aged 18-49 years with an isolated focal cartilage defect in the knee will be randomized to either receive autologous cartilage implantation or arthroscopic debridement. Both groups will then undergo a systematic physiotherapy training regime for 6-9 months. The Groups will then be compared for results, after 3, 6, …

18 - 49 years of age Both Phase N/A

Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction

A randomized controlled clinical study was conducted to elucidate the relationship between the lower extremity biomechanics of patients undergoing early gait training after ACLR surgery.The relationship between the biochemical characteristics of cartilage and the biomechanical risk index were proposed to providing exercise guidance and training for middle-aged people and it …

18 - 40 years of age Both Phase N/A
L Lore Hermans, MSc

Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant

The goal of this study is to evaluate the efficacy, safety and performance of the Episealer® device in a sample size of 30 patients and on the long term (10 years follow-up).

18 - 100 years of age Both Phase N/A
J Joseph Laurent

The Hyalex Early Feasibility Study (EFS)

The Hyalex Early Feasibility Study is a prospective, multicenter, open-label, single-arm, 2-phase early feasibility study to evaluate the safety and technical performance of the HYALEX Knee Cartilage System for replacement of loss of articular cartilage and bone of the knee femoral condyles in symptomatic patients who require surgical treatment, will …

21 - 70 years of age Both Phase N/A
Y Yanyan Jia

Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis

To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for the treatment of joint injury.

20 - 60 years of age Both Phase N/A
K Kerstin Hofschulz

Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee

Multi-center, prospective, concurrently controlled, non-randomized, double-blind (patient and assessor). Treatment of large chondral lesions in the knee with microfracture plus the Chondro-Gide® ACC is non-inferior to treatment of small chondral lesions treated with microfracture alone.

18 - 55 years of age Both Phase N/A
J Jacob G Calcei, MD

Impact of Mesenchymal Stem Cells in Knee Osteoarthritis

Many patients with osteoarthritis of the knee fail non-operative measures and elect to have knee arthroplasty to improve their quality of life. If successful, intra-articular mesenchymal stem cell (MSC) injections into the knee may offer another viable non-operative treatment modality. Additionally, this modality may have reparative or regenerative potential, which …

18 - 60 years of age Both Phase 1
A Alessandro Di Martino, MD

The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction

The aim of the study is the evaluation of both clinical and radiological results in patients undergone to cruciate ligament reconstruction with concomitant cartilaginous lesion treated with or without nanofractures.

18 - 55 years of age Both Phase N/A

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