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Rectal Disorders Clinical Trials

A listing of Rectal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 686 clinical trials
M M. Koopman, dr.

Prospective Data Collection Initiative on Colorectal Cancer

Survival after colorectal cancer (CRC) diagnosis strongly depends on local tumor extent, lymph node involvement and the presence of distant metastases. However, there remains great inter-patient variability regarding treatment outcome. A combination of biochemical factors, histopathological features, genomic profile, environmental factors and other clinical factors are likely to influence prognosis …

18 years of age All Phase N/A
K Kjetil Søreide, MD, PhD

Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer

A prospective, observational study on clinical outcomes of surgical management of primary and metastatic colorectal cancer Prospective collection of tissues to explore potential biomarkers in blood and/or primary or secondary cancers and/or normal colon

18 years of age All Phase N/A

ALFAOMEGA Master Observational Trial

AlfaOmega has been designed to streamline the study of the co-evolutionary landscape between tumor and host cells in a cohort of CRC patients, with the aim of understanding how their outcomes can be significantly improved (e.g. reduction of their chance of recurrence and survival improval). This clinical resource for integrative …

18 years of age All Phase N/A
H Hsiang-Chi Chen

Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

TRACC Part B This is a multi-centre, prospective, translational research study involving the collection and analysis of tumour tissue, serial blood samples and clinical data in patients with newly diagnosed stage I, II and III CRC. TRACC Part C is a : (multi-centre, prospective, randomised study, of ctDNA guided adjuvant …

18 years of age All Phase N/A

Epidemiological and Molecular Colorectal Cancer Registry

This is a Registry that invites patients undergoing colorectal surgery for colorectal cancer. Epidemiological data is collected. The Registry includes tumor tissue and blood banks for analyzing different genetic mutations and disease-specific biomarkers.

21 - 96 years of age All Phase N/A
S Samir Gupta, MD MS

Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study

Colorectal cancer is a leading cause of cancer death. Detection and removal of polyps can reduce risk for developing colorectal cancer. After finding and removing precancerous polyps, repeat colonoscopy is routinely recommended. However, it is unclear whether repeat additional colonoscopy further reduces risk for colorectal cancer. For older adults age …

75 years of age All Phase N/A
K Kefeng Ding, MD

the National Colorectal Cancer Cohort (NCRCC) Study: National Colorectal Cancer Research Consortium

NCRCC study is a national prospective cohort study including colorectal cancer screening population and stage Ⅰ-Ⅳ colorectal cancer patients.

18 years of age All Phase N/A
L Line Fly, MD

SMARTER: Using Blood Samples to iMprove FIT-bAsed coloRecTal cancEr scReening

The project aims to investigate whether colorectal cancer screening can be improved using blood tests, thereby reducing the number of unnecessary colonoscopies. The Danish colorectal cancer screening program was implemented in 2014, and currently, all individuals aged 50-74 are invited every two years to participate. Those who test positive for …

50 - 74 years of age All Phase N/A

COlorectal BReath Analysis (COBRA2)

Colorectal cancer (CRC) is the second most common cause of cancer death in the United Kingdom, with approximately 17,000 deaths per year. The five-year survival rate from CRC is only 10% when discovered at a late stage, but exceeds 90% if diagnosed early. Symptoms related to CRC can be non-specific, …

18 - 90 years of age All Phase N/A
G Gianluca Ianiro, MD

Microbiome-based Diagnostic Tool for the Screening of Colorectal Cancer (GUILTI)

Colorectal cancer (CRC) is one of the most common cancer and cause of cancer death worldwide. Population-based screening programs for average risk populations have proven effective in reducing both incidence and mortality of CRC through early detection of cancer. The fecal immunochemical testing (FIT), has still a suboptimal diagnostic yield, …

50 - 74 years of age All Phase N/A

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