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spinal-muscular-atrophy Clinical Trials

A listing of spinal-muscular-atrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 76 clinical trials

Safety and Usability of a Robotic Gait Device for Children and Adolescents With Neurological or Neuromuscular Disease in Their Natural Environment

The goal of this clinical trial is to analyze the usability and safety of the robotic gait device EXPLORER in children with cerebral palsy, acquired brain injury and spinal muscular atrophy. Participants will use the exoskeletons in their home and the community and variables regarding safety and usability will be …

2 - 17 years of age Both Phase N/A
B Betts Peters, PhD

Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit

This project adds to non-invasive BCIs for communication for adults with severe speech and physical impairments due to neurodegenerative diseases. Researchers will optimize & adapt BCI signal acquisition, signal processing, natural language processing, & clinical implementation. BCI-FIT relies on active inference and transfer learning to customize a completely adaptive intent …

18 - 89 years of age Both Phase N/A
M Mena Scavina, DO

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one arm sufficient to perform daily activities. This study could lead to …

4 - 100 years of age Both Phase N/A
P Patricia Graham, MS, CCRC

Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)

This study will evaluate if Ursolic Acid supplementation may be effective in reducing muscle loss and improving blood sugar control in the SCI community.

18 - 65 years of age Both Phase 2

Measurement of the Optic Nerve Sheath Diameter

This study is a prospective assessment of the accuracy of ocular ultrasound as a tool to measure the diameter of the optic nerve sheath and the eyeball transverse diameter in healthy adult patients presenting to the Emergency Department and have confirmatory imaging of the optic nerve as part of their …

18 - 100 years of age Both Phase N/A
S Study Team

Hyperbaric Oxygen Therapy for Optic Neuropathies

The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.

18 - 100 years of age Both Phase N/A
S Study Team

Electrical Stimulation for the Treatment of Optic Neuropathies

The overall aim of this study is to see whether long-term electrical stimulation with a home-stimulation device works well and is safe for the treatment of open-angle glaucoma. Open-Angle Glaucoma is a disease where the nerves in the back of your eye die off faster than expected regardless of your …

18 - 100 years of age Both Phase N/A
N Neil Lagali

Alternating and Direct Current Stimulation for Neuropathic Eye Pain

The goal of this clinical intervention is to test if two forms of transcranial current stimulation, transcranial direct current stimulation (tDCS) or transcranial alternating current stimulation (tACS) can alleviate neuropathic eye pain in a sample of 20 patients. The main aims are: Test if tDCS/tACS can alleviate neuropathic eye pain …

18 - 100 years of age Both Phase N/A
T Tao Jiang, MD and PhD

Accelerating Motor Recovering in Patients With SMA Syndrome After Glioma Surgery by Using nrTMS

The goal of this randomized clinical controlled trial is to learn about whether neuro-navigation repetitive transcranial magnetic stimulation (nrTMS) was useful to accelerate the recovery in patients with SMA syndrome after glioma resection. The main questions aim to answer: Question 1: Whether the nrTMS was useful to accelerate the recovery …

25 - 55 years of age Both Phase N/A
S Steven Levy, MD

Stem Cell Ophthalmology Treatment Study II

This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.

18 - 100 years of age Both Phase N/A

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