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weight-loss Clinical Trials

A listing of weight-loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 155 clinical trials
S Sharon O'Toole, M.A.T.

Control Systems Engineering for Weight Loss Maintenance

This project capitalizes on principles of control systems engineering to build a dynamical model that predicts weight change during weight loss maintenance using behavioral, psychosocial, and environmental indicators evaluated in a system identification experiment. A 6-month behavioral obesity treatment will be administered to produce weight loss. Participants losing at least …

18 - 70 years of age All Phase 2
N Nouf Alfouzan

Food Cravings Strategies During Dietary Weight Loss

The purpose is to optimize the EMPOWER program by integrating strategies to reduce food cravings, a critical yet often overlooked factor for long-term success in weight management. The objective of this study is to determine the efficacy of craving coping strategies on weight loss outcomes by conducting a randomized controlled …

18 - 75 years of age All Phase N/A
C Camille S Worthington, PhD

Time-restricted Eating for Postpartum Weight Loss

This study is being done to assess the feasibility and acceptability of a time-restricted eating intervention among postpartum women with overweight/obesity.

18 years of age Female Phase N/A
B Bin Li, MD

Thread Embedding Acupuncture Therapy for Weight Loss

Obesity is the most prevalent chronic disease worldwide, affecting approximately 800 million adults. Excess adiposity and its numerous complications, including cardiovascular disease and type 2 diabetes, impose a considerable economic burden and constitute major contributors to global morbidity and mortality. Treatments that result in substantial weight reductions may improve outcomes …

18 - 75 years of age All Phase N/A
J Jenny Ho

BEAM for Weight Loss - a Pilot Study

Bariatric endoscopic antral myotomy (BEAM) is a novel endoscopic technique which is performed using a gastroscope under general anesthesia. It involves cutting the muscle fibers at the gastric antrum, thereby weakening the antral pump, delaying gastric emptying and inducing satiety. Early reports had shown that this technique can produce significant …

18 - 70 years of age All Phase N/A
H Huijie Zhang, MD. PhD.

Intermittent Eating on Sustaining Weight-loss in Obesity

Weight regain after weight loss is a major problem in the treatment of obesity. Two novel types of intermittent fasting recently have received more attention: the 5:2 diet and time-restricted eating (TRE). TRE requires individuals to eat in a specified number of hours per day (typically 4 to 10 hours) …

18 - 75 years of age All Phase N/A
M Mohamed Abeid, MD

Endo-Band: Endoscopic Band Ligation for Weight Loss

To the best of our knowledge, this is the first study to use endoscopic band ligation for weight loss. All ligatures will be performed in the gastric body starting at the distal body; 5 parallel rows, with the last one in the proximal body.The entire procedure can be completed in …

18 - 65 years of age All Phase N/A
S Sara Maskal, MD

Preoperative Weight Loss for Open Abdominal Wall Reconstruction

The goal of this randomized controlled trial is to compare preoperative intensive weight management to upfront surgery in obese patients undergoing complex abdominal wall reconstruction. The main question is will abdominal wall specific quality of life (using the HerQLes survey) for the group undergoing upfront surgery be non-inferior compared to …

18 years of age All Phase N/A
M Meghan L Butryn, PhD

Piloting a Patient Navigator Program for Weight Loss

Evidence-based interventions for overweight and obesity are underutilized. The utilization and efficacy of these interventions may improve with the implementation of a patient navigator program, as has been practiced in other fields (e.g., cancer). The proposed study will enroll adults ("index participants") (N=68) with overweight/obesity in a 12-month program in …

18 - 75 years of age All Phase N/A
P Page E Blas, MA

Tirzepatide Weight Loss for MRD+ Early Breast Cancer

This trial aims to asses if tirzepatide-induced weight loss will lead to metabolic and hormonal changes in hormone receptor-positive (HR+), human epidermal growth factor receptor-negative (HER2-), node-positive (N+) high risk early breast cancer patients with obesity or overweight, inhibiting the growth and survival of micrometastatic disease and leading to clearance …

18 years of age All Phase 2

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