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weight-loss Clinical Trials

A listing of weight-loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 170 clinical trials
C Chun-Ying Wu

The Efficacy of Weight-loss Diet Decision-making Based on Initial Gut Metabolic Modules (GMMs)

In recent years, the technology to detect the gut microbiome's function has become increasingly developed. GMMs are tools (GitHub - raeslab/GMMs: A manually curated database of human gut metabolic modules.) for describing metabolic pathways for linking microbial metabolic function to species associated with a single metabolite, helping to analyze the …

20 - 64 years of age Both Phase N/A
M Marya Schulte, PhD

BrainWeighve Weight Loss App

Childhood obesity within the United States has been a growing concern over the past number of years, and if not addressed, leads to detrimental health outcomes for youth as they move into adulthood. The literature suggests that over-eating, especially when framed in terms of food addiction, plays a key role …

14 - 18 years of age Both Phase N/A

Weight Loss and Physical Fitness Following Pregnancy in Active Duty Women

Pregnancy and delivery are major stressors on the female body and contribute significantly to permanent weight gain and associated morbidity in women. This can profoundly affect the ability of active duty (AD) women to advance in their career. The first 12 weeks postpartum are the time period during which the …

18 - 44 years of age Female Phase N/A
L Linda Bunyard, MS, RD

Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions

The objective of the HELPLINE Weight Loss Program is to determine the comparative effectiveness of two active multi-component, augmented interventions for cancer survivors with overweight or obesity who do not achieve early weight loss goal in the initial intervention period (termed, early non-responders). The core study design is randomized controlled …

18 - 100 years of age Both Phase N/A

Effect of Phaseolus Vulgaris L. Dry Extract on the Modulation of Weight and Metabolic Parameters

Evaluation of the efficacy of Phaseolus vulgaris L. dry extract on weight modulation.

18 - 60 years of age Male Phase N/A
L Lauren Martin, MS

Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery

Bariatric surgery is an effective treatment for severe obesity but results in loss of muscle mass. The investigators will test the hypothesis that consumption of an Essential Amino Acid-based nutritional formulation will maintain muscle mass while stimulating fat loss after bariatric surgery.

18 - 60 years of age Both Phase N/A
S Stephanie Kullmann, PhD

Effect of Weight Loss on Brain Insulin Sensitivity in Humans

Obesity if known to be associated with brain insulin resistance in humans. This condition has not only implication for the brain but also for whole-body energy homeostasis. Research in rodents indicates that weight loss is able to improve insulin sensitivity of the brain. The current project will test this hypothesis …

40 - 75 years of age Both Phase N/A
E Elizabeth A Lawson, MD

Oxytocin for Weight Loss in Adolescents

This is a randomized, double blind, placebo-controlled study of the effects of intranasal oxytocin in youths with obesity, ages 12-18 years old. Subjects will be randomized to receive intranasal oxytocin or placebo (3 sprays per nostril, 4 times per day) for 12 weeks. Study visits include screening to determine eligibility, …

12 - 18 years of age Both Phase 2

Combining Chinese Medicine and Nutrition to Enhance Weight Loss After Bariatric Surgery

This study aims to investigate the effects of Chinese herbal granule preparations on improving gastrointestinal symptoms in patients after bariatric surgery. It seeks to establish a novel treatment model that combines bariatric surgery with traditional Chinese medicine, providing clinical practice with additional evidence-based medical support.

18 - 65 years of age Both Phase N/A
R Raymond M Panas, PhD MPH

Coach to Fit Weight Loss Intervention for Individuals With Serious Mental Illness

This project addresses obesity in the population with SMI by evaluating a weight management program that is not only evidence-based, it is sustainable, transportable, appealing to patients, easy to use, and minimally burdensome to the healthcare system. This effort addresses two HSR&D priority areas: 1) Mental Health: Testing new models …

18 - 100 years of age Both Phase 3

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