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lower-back-pain Clinical Trials

A listing of lower-back-pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 281 clinical trials
B Bart Koes, Prof. Dr.

Efficacy of Antibiotic Treatment for Patients With Chronic Low Back Pain and Modic Type I Changes - Randomized Placebo-controlled Trial

The goal of this clinical trial is to learn if antibiotics (amoxicillin) work to treat chronic low back pain in adults. In some patients, this type of back pain may be caused by bacteria in the vertebrae, resulting in a condition known as "Modic type I change." The main questions …

18 - 65 years of age All Phase 3
D Divya Adhia, Ph.D

Brain Network Stimulation for Chronic Low Back Pain.

This study looks at the non-invasive brain stimulation technique in people with chronic low back pain to see: How effective non-invasive brain stimulation is at improving pain intensity in people with chronic low back pain? How safe non-invasive brain stimulation is and what side effects there may be? What study …

18 - 75 years of age All Phase N/A
J Jean Tittley, MSc

Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain

Chronic low back pain (CLBP) is a major health challenge in Canada, leading to substantial disability and socioeconomic burden, particularly among Veterans. In military Veterans, LBP is the most common chronic pain condition. Conventional interventions have limited effectiveness. The refractoriness to interventions suggests that specific CLBP mechanisms may be missed …

18 - 65 years of age All Phase N/A
A Asma A Alqahtani, B.S.C

Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain

Randomized control trial to examine the immediate effect of isometric exercise on pressure pain threshold (PPT) in adults with chronic low back pain. The secondary aim of this study was to investigate the acute effects of isometric exercise on clinical pain intensity.

18 years of age All Phase N/A
A Arnold Wong, PhD

Acceptance and Commitment Therapy Plus Exercise for Older People With Chronic Low-back Pain: A Pragmatic Cluster Randomised Controlled Trial

Low back pain (LBP) is the fifth-most common disorder among older adults 60 years or older. The prevalence of LBP increases with age, with the highest prevalence occurring at 85 years old. Because many older individuals face various age-related life challenges (e.g., comorbidities, financial difficulties, and bereavement), the addition of …

60 years of age All Phase N/A
F Fadi MQ Al Zoubi, PhD

Expressive Art Therapy for Elder Adults With Chronic Low Back Pain

This research project aims to assess the feasibility of expressive art therapy for elderly adults with chronic low back pain and to evaluate the preliminary efficacy of combining art therapy with exercise intervention. Additionally, the study will investigate facilitators and barriers to participation. A mixed-methods approach will be employed, including …

60 years of age All Phase N/A
P Philippe METELLUS, MD

Evaluation of the Benefit and Safety of Localized Tissue Hydration in the Management of Chronic Low Back Pain

The purpose of this study is to evaluate the benefit of Localized Tissue Hydration associated with standard management of chronic common low back pain, in terms of improvement in the numerical verbal scale score at 6 months.

18 years of age All Phase 2

Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.

The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving conventional medical management (CMM) techniques.

18 years of age All Phase N/A
I Irene Torres-Sánchez, PhD

Effects of Pain Neuroscience Education and Virtual Reality in Patients with Chronic Low Back Pain

The objective of our study is to evaluate the effects of a therapeutic intervention including 1-hour of pain neuroscience education session, 30-minutes of exposure to exercise with virtual realit and therapeutic exercise in patients with chronic low back pain.

18 - 65 years of age All Phase N/A
S Steven Pratscher, PhD

Integrative Breathwork Intervention for Chronic Pain

The proposed research is to develop and refine a multicomponent breathwork intervention, Guided Respiration Mindfulness Therapy, and to iteratively evaluate its feasibility, acceptability, and plausibility for clinically significant effects in people with chronic low back pain. This integrative breathwork intervention involves a 60-minute breathing session where the focus is to …

18 - 70 years of age All Phase 1/2

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