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Cardiac Ischemia Clinical Trials

A listing of Cardiac Ischemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 744 clinical trials
S Suk Ho Sohn, MD

Effect of Left Posterior Pericardiotomy for the Prevention of POAF

This study is planned to evaluate the effect of left posterior pericardiotomy for the prevention of postoperative atrial fibrillation after coronary artery bypass grafting. Eligible patients will be randomized to be created or not to be created the left posterior pericardiotomy at the end of the operation, and the incidence …

19 years of age All Phase N/A
J Jakub Drozd

Antegrade Dissection and Re-entry Versus Retrograde Strategy in CTO PCI

The ADRENALINE trial has been designed as a multi-center, prospective randomized study to compare the procedural and periprocedural outcomes of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using antegrade dissection and re-entry (ADR) versus retrograde strategy. Beyond the patient-oriented outcomes, the influence of the studied CTO PCI strategies …

18 years of age All Phase N/A
C Cezary Kępka, MD PhD

Effects of Switching From Cigarettes to Tobacco Heating System on Coronary Atherosclerosis Progression

Objective To evaluate the impact of heated versus combustion tobacco products on progression of atherosclerosis in patients with CAD unable(unwilling) to quit smoking. Rationale Despite the efforts to curb smoking and full awareness of its deleterious health impact, smoking remains a significant contributor to morbidity and mortality. Some health impact …

18 - 75 years of age All Phase N/A
N Nick M Naughton, BS

Bright Light Exposure in Surgical Patients

Elucidate the influence of intense light therapy pretreatment in patients undergoing cardiac surgery. We hypothesize that intense light exposure is associated with the peripheral stabilization of Per2 in human buccal swabs and plasma samples before surgery and with a decrease of Troponin I levels after surgery. In addition, we hypothesize …

18 - 90 years of age All Phase N/A
D Denise White

Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia

This study is being done to observe the effects of treatment from a device called the Bioboosti which utilizes pulsed electromagnetic waves on its ability to improve blood flow to the heart tissue in individuals with coronary artery disease (CAD).

18 years of age All Phase N/A
N Nicci Thompson

TECTONIC CAD IVL IDE Study

A prospective, single-arm, open-label, multi-center IDE study with up to 55 US sites

18 years of age All Phase N/A
N Nikita Grishin

Temporary MCS With the iVAC 2L Transaortic Device in High-risk PCI

Patients with coronary artery disease and undergoing high-risk percutaneous coronary intervention (PCI) are at increased risk of hemodynamic instability and poor outcomes. Mechanical circulatory support (MCS) devices may offer hemodynamic stabilization during PCI, potentially improving short- and long-term outcomes. The study rationale is to investigate the safety and clinical efficacy …

18 years of age All Phase N/A
D Dominik P Guensch, MD

Influence of Oxygen on Perioperative Outcome in Patients Undergoing General Anaesthesia for Elective Non-cardiac Surgery

The purpose of this study is to investigate the impact of supraphysiologic oxygen (hyperoxia) on myocardial function in anaesthetized patients undergoing non-cardiac vascular surgery.

18 years of age All Phase N/A
M Mary Zhang, MD, PhD

REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial

Ischemic mitral regurgitation (MR) and coronary artery disease is common and associated with significant morbidity and mortality. Ischemic MR has been traditionally treated surgically through either valve repair or replacement at the time of concomitant bypass grafting. Although patients with ischemic MR represent a heterogeneous group, outcomes for these patients …

18 years of age All Phase N/A

Intrapleural Ropivacaine Infusion in Cardiac Surgery

For many patients, a primary source of postoperative pain following cardiac surgery is the presence of pleural drains, which the surgeon places at the end of the operation and maintains for 1 to 3 days. One promising method of pain management after cardiac surgery is interpleural analgesia, particularly when traditional …

18 years of age All Phase 4

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