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Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 267 clinical trials
H Hui-Hsuan Lau, PhD

Comparing Treatments for Overactive Bladder in Taiwan: A Study of Outcomes

Overactive bladder (OAB) syndrome is a prevalent condition that significantly impairs patients' quality of life. Standard therapeutic strategies include oral antimuscarinics (e.g., solifenacin), beta-3 adrenergic agonists (e.g., mirabegron), and intradetrusor injection of botulinum neurotoxin type A (BoNTA). Despite their clinical utility, these treatments share a common mechanism of action: suppression …

30 - 100 years of age Female Phase N/A
W Women's Health Research Unit

At-Home Transcutaneous Tibial Nerve Stimulation for Overactive Bladder in Rural Women

This study contains a mixed-methods design consisting of a single-arm, interventional study and prospective patient interviews evaluating a novel self-implemented at-home Transcutaneous Tibial Nerve Stimulation (TTNS) treatment protocol for management of treatment naïve overactive bladder (OAB) among rural-dwelling women. This study will be conducted in 3 rural Oregon communities where …

18 years of age Female Phase N/A
T Tracy Liaw

INOPASE - Performance and Safety Study of a Personalised SNM System

The goal of this clinical trial is to learn whether a new sacral neuromodulation (SNM) system (INO-SNM-01) can safely and effectively sense bladder nerve activity and provide stimulation to help manage symptoms of refractory overactive bladder in adult women aged 18-70 who have not responded to standard treatments. The main …

18 - 70 years of age Female Phase N/A
M Maria Parco

Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

A study to evaluate the safety and effectiveness of FemPulse System

21 years of age Female Phase N/A
z zehra korkut

Investigation of Effects of Electrical Stimulation in Women With Vaginal Laxity

The purpose of this study is to compare the effects of different externally applied electrical stimulation methods on overactive bladder (OAB) symptoms, quality of life, and patients' perception of improvement.

18 - 65 years of age Female Phase N/A
J Julia Geynisman-Tan, MD

Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function

This is a pilot study to assess using validated outcome measures how ingesting pumpkin seed oil extract supports patient bladder function in a United States population.

18 years of age Female Phase N/A
Y Yike Lui

Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation

Electrical stimulation of the sacral nerve can help with bladder problems and pelvic pain but researchers don't understand exactly how the stimulation helps. The goal of this study is to examine signals evoked during sacral neuromodulation (SNM or electrical stimulation of the sacral nerve) and their relationship to the selection …

18 years of age All Phase N/A
C Claire MORANDO

EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS

The purpose of this study is to evaluate the effectiveness and safety of a minimally invasive surgical procedure with ACT (Adjustable Continence Therapy) balloons implantation for the treatment of urinary incontinence in children with bladder exstrophy or isolated epispadias. The ACT therapy consists of two small adjustable silicone balloons connected …

5 - 18 years of age All Phase N/A
I Inger Ljungberg, MPH

Intravesical Lactobacillus for Urinary Symptoms Among People With NLUTD Who Use Indwelling Catheters

The objectives of the proposed research among this population are: 1) to define clinically meaningful change (i.e. differentiating states of health and illness) with respect to urinary symptoms, urine inflammation, cultivable bacteria, and the urine ecosystem; and 2) to determine the optimal intravesical Lactobacillus RhamnosusGG (LGG®) dose to be used …

18 years of age All Phase 2
J Jesica L-G Leal García, PhD Student

Effect of Neuromodulation and Therapeutic Exercise in Urinary Incontinence

Urge urinary incontinence (UUI) is a component of the condition known as overactive bladder, a severe and debilitating chronic disorder affecting healthcare systems worldwide. The efficacy of therapeutic exercise and neuromodulation in the treatment of UUI is evaluated, and these techniques are combined.

45 years of age Female Phase N/A

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