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Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,512 clinical trials

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

This is a multicenter, randomized, double-blind, placebo-controlled, Phase 3 study designed to compare the efficacy and safety of tislelizumab + either cisplatin or carboplatin + gemcitabine versus placebo+ either cisplatin or carboplatin + gemcitabine in approximately 420 participants with locally advanced or metastatic urothelial carcinoma who have not received prior …

18 - 75 years of age All Phase 3
D Dr Bal Krishna Mishra, MD

Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients

This is a randomized, open-label, two-arm, Phase III clinical trial evaluating the efficacy and safety of trastuzumab plus chemotherapy versus chemotherapy alone as first-line treatment in patients with HER2-positive advanced or metastatic biliary tract cancers (BTC). HER2-positive BTCs represent a molecular subset of these rare cancers, associated with poor prognosis …

18 - 99 years of age All Phase 3
P Pohung Lin

The Impact of Social Media-delivered Chemotherapy Side Effects Education for Breast Cancer Patients Receiving Chemotherapy

The goal of this clinical trial is to learn if a standardized pharmacists-provided education module by social media can improve patients' knowledge of chemotherapy-related side effects. The main questions it aims to answer is: • Do patients who received a standardized pharmacists-provided education module by social media improve their knowledge …

18 years of age All Phase N/A
M Medical College of Wisconsin Cancer Center Clinical Trials Office

Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial

This is an open-label, phase II study in patients with resectable and borderline resectable pancreas cancer.

18 years of age All Phase 2
H Herve Bonnefoi, Prof.

Circulating Tumor DNA After Neoadjuvant Chemotherapy

Trial assessing the prognostic value of ctDNA mutations from samples taken sequentially in patients with invasive breast cancer initially treated with neoadjuvant chemotherapy and whose tumor is not in complete histological response.

18 years of age All Phase N/A

Quality of Life Improvement During Chemotherapy

This study is a randomized controlled trial, taking place at the University Hospital Basel (CH). It aims at the alleviation of breast cancer patients' life quality during chemotherapy. The intervention group will participate in 10 sessions of structured hypnotherapy during the course of chemotherapy in addition to the standard of …

18 years of age Female Phase N/A
E Elisa Konofagou, PhD

Breast Elasticity Imaging During Neoadjuvant Chemotherapy

For this study, the investigators propose investigation of a new imaging technique, Harmonic Motion Imaging (HMI), and the evaluation of its potential role in prediction of breast cancer response to neoadjuvant chemotherapy (NACT). The investigators hypothesize that changes in HMI parameters will predict response to neoadjuvant systemic therapy in early-stage …

18 years of age Female Phase N/A
B Bruno Nervi, MD

Telemonitoring Platforms and Chemotherapy-Associated Toxicity

The primary objective of this trial is to evaluate the impact of a telemonitoring platform on patient satisfaction with care amongst adult cancer patients receiving chemotherapy. The key questions it seeks to address revolve around the potential improvements in both quality of life and satisfaction with healthcare. Participants in the …

18 years of age All Phase N/A
G Glenn J Hanna, MD

Toripalimab With Chemotherapy for Sinus Cancer

The aim of this research study is to evaluate the effectiveness and safety of a combination of immunotherapy, using a drug called toripalimab, with chemotherapy drugs, Carboplatin and Docetaxel, as a possible treatment before surgery for sinonasal cancers. The names of the study drugs used in this research study are: …

18 years of age All Phase 2
Y Young-Joon Kang, PhD

AI-Assisted Chemotherapy Side Effect Management

This two-stage adaptive randomized controlled trial evaluates the feasibility and preliminary efficacy of large language model (LLM)-assisted intervention for managing chemotherapy side effects in patients with solid tumors. Adults with histologically confirmed breast or colorectal cancer scheduled for at least 3 months of systemic chemotherapy will be randomly assigned (1:1) …

18 years of age All Phase N/A

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