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moyamoya-syndrome Clinical Trials

A listing of moyamoya-syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 18 clinical trials
J Jinhao Lyu, MD

The Evolution and Prognosis of Moyamoya Disease

To investigate the evolution of imaging appearances and cognitive function of Moyamoya disease (MMD) and to establish a prognosis evaluation system based on imaging biomarkers in MMD. The study may be helpful to optimize and improve the diagnosis and pretreatment assessment of MMD, and provide an important theoretical supplement to …

10 - 60 years of age All Phase N/A
G Gabriella Morton, BS

Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease

The goal of this study is to study the incidence of post-operative Transient Neurologic Events (TNEs) within 30 days postoperatively, as assessed by clinical neurological scales, binned by week. Collect data on all interventions and assessments performed during the recovery post surgery up to 30 days, to understand what factors …

3 years of age All Phase N/A
Q Qian Zhang, MD

Study on the Mechanism of Cognitive Impairment in Patients with Moyamoya Disease

The purpose of this study is to comprehensively evaluate the risk factors for cognitive decline in patients with moyamoya disease, identify imaging target areas associated with cognitive damage in the brain, and explore the changes in brain structure and functional networks resulting from cerebral revascularization, as well as their relationship …

18 - 60 years of age All Phase N/A
Q Qian Zhang, MD

Study on Evaluating the Effectiveness of Statins in the Treatment of Moyamoya Disease

The purpose of this study is to investigate the effectiveness of statins in the treatment of moyamoya disease based on multimodal magnetic resonance imaging.

18 - 60 years of age All Phase N/A
S Shu Li, M.D.

Functional Magnetic Resonance-Based Observations of Brain Networks in Moyamoya Disease Patients Under Anesthesia

Moyamoya disease is characterized by progressive stenosis of the genesis of the distal internal carotid arteries bilaterally and progressive generation of compensatory pathological vascular networks at the basis cranii, and these pathological vasculature has poor vascular reactivity. Perioperative circulatory management of patients with smoky vessels to ensure perfusion of brain …

18 - 65 years of age All Phase N/A

Long-term Outcomes of Conservative Management in Patients With Moyamoya Disease and Their First-degree Relatives (LAMORA)

The purpose of this study is to investigate the long-term outcomes of conservative management in patients with moyamoya disease and their first-degree relatives, and provide potential pathogenesis of moyamoya disease.

2 - 60 years of age All Phase N/A
E Elena MESEGUER, Dr

Super-resolution Clinical Brain Ultrasound

Transcranial Doppler ultrasonography with injection of contrast agent (intravenously to enhance the ultrasound signal) is a non-invasive technique that has been used for years to study intracranial vessels that constitute the polygon of Willis. However, this technique does not allow good visualization of small vessels, such as perforating arteries. Ultrasound …

18 years of age All Phase N/A
L Luigi Grimaldi, MD

RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)

Cerebrovascular diseases (CVDs) are one leading cause of morbidity and mortality worldwide. Despite intensive investigations, more than 30% of strokes remain of undetermined origin. Rare Cerebrovascular Diseases (rCVDs), including heritable (i.e., CADASIL, COL4A1 syndrome, Fabry disease) and acquired conditions (i.e., Sneddon syndrome, Moyamoya arteriopathy) account for a proportion of these …

18 years of age All Phase N/A

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