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Cataracts Clinical Trials

A listing of Cataracts medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 125 clinical trials
X Xuanqiao Lin

Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts

The goal of this observational study is to compare the mid- to long-term efficacy of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in patients with moderate to severe Fuchs' endothelial corneal dystrophy (FECD) complicated by cataracts. The main questions it aims to answer are: Does FLACS lead …

40 years of age All Phase N/A
A Alana K Dunn

Effective Phaco Time and Endothelial Cell Loss When Using Veritas

This study is a single center, prospective study of cumulative dissipated energy and endothelial cells loss per phacoemulsification procedure after successful cataract surgery. Subjects will be assessed 3 months postoperatively at a single visit. Clinical evaluations will include central corneal thickness, specular microscopy, as well as measurement of visual acuities …

years of age All Phase N/A

Capella Scientia Development Study

This study involves collecting biometry and aberration data using the next generation biometer, Unity DX.

18 years of age All Phase N/A
Z Zoe Baker, OD

Outcomes of Clareon PanOptix in Patients With Prior Myopic Refractive Surgery

This study is a Single center, single arm, prospective, observational study of clinical outcomes following bilateral cataract surgery and Clareon PanOptix implantation. Subjects will be assessed preoperatively, and at 1 and 3 months postoperatively. Clinical evaluations will include administration of the QUVID and IOLSAT questionnaires, manifest refraction, topography, as well …

45 years of age All Phase N/A
z zeliha tuncel, ass prof

General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery

The primary aim of the study is to investigate the correlation between preoperative hemodynamics and frailty scores in patients undergoing cataract surgery under general anesthesia. The secondary objective is to explore the relationship between preoperative and postoperative intraocular pressure changes and frailty scores.

65 - 85 years of age All Phase N/A
X Xuanqiao Lin

Performance of Large Language Models for Structured Recognition and Refractive Prediction

We conducted a single-center, retrospective observational study to evaluate large language models (ChatGPT 4o, GPT-5, DeepSeek) for automated interpretation of de-identified IOLMaster 700 reports provided as raster images. Models produced structured biometric extraction, toric IOL recommendation, and refractive predictions (sphere, cylinder, axis). Primary outcomes included parameter-level agreement and refractive error …

18 years of age All Phase N/A
A Allison Hales

Refractive Outcomes Utilizing Two SS-OCT Biometers for IOL Power Calculations

The purpose of this study is to evaluate and compare the potential refractive outcomes using the Argos 1.5 biometer in the surgical planning for cataract extraction to that obtained from IOLMaster 700. Both devices are used as standard of care in surgical planning optimization for patients undergoing cataract surgery.

21 years of age All Phase N/A
J Jin Yang, PhD

The Molecular Pathogenesis Study of Cataract

To study the molecular pathogenesis of cataract and explore possible treatments,anterior lens capsules were collected from cataract patients

18 - 90 years of age All Phase N/A
X Xuanqiao Lin

Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery

This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract. Key outcomes include best-corrected visual acuity, stereopsis, refractive error, and axial length growth. The study will help identify long-term trends and prognostic indicators after early cataract intervention in …

- 18 years of age All Phase N/A
J Jin Yang, PhD

Effectiveness, Stability and Influence Factors of Femtosecond Laser Assisted Cataract Surgery

What is this study about? This study looks at whether a laser procedure called femtosecond laser-assisted arcuate keratotomy (FSAK) helps people with both cataracts and mild astigmatism see more clearly after cataract surgery. Astigmatism causes blurry vision because the front of the eye (cornea) is curved unevenly. The FSAK procedure …

20 - 80 years of age All Phase N/A

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