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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,180 clinical trials
M Mingwei Ma

SABR Combined with Axitinib and Toripalimab in Recurrent or Metastatic RCC

This is a prospective, single-center clinical trial designed to evaluate the safety and efficacy of combining stereotactic ablative body radiotherapy (SABR) with the targeted therapy Axitinib and the immunotherapy Toripalimab in patients with recurrent metastatic renal cell carcinoma (RCC). Patients will receive a treatment regimen consisting of Axitinib, Toripalimab, and …

18 - 80 years of age All Phase 2
F Feng Wang, phD

Safety and Efficacy of SHR2554 Combined With Other Antitumor Therapies in Gastric or Gastro-oesophageal Junction Adenocarcinoma

This is a multicenter, phase 2, open label study to evaluate safety, tolerability and efficacy of SHR2554 combined with other anti-tumor treatments in patients with advanced or metastatic gastric or gastroesophageal junction adenocarcinoma.

18 - 75 years of age All Phase 2
S ShaoChung Wang, PhD

Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in HNSCC Patients

This project adopts a prospective study design. It is scheduled to enroll 60 participants diagnosed with Head and Neck cancer in this hospital, of which 30 are in the experimental group and 30 are in the control group. The purpose of this research is to analyze the skeletal muscle mass …

20 - 80 years of age All Phase N/A
M Margaret McNeely, PhD

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

Trismus, or restricted jaw movement, can occur in individuals with head and neck cancer (HNC) undergoing surgery or radiation therapy. There is a paucity of research examining interventions for trismus. We aim to assess the feasibility of prospective surveillance and early intervention to mitigate trismus in individuals undergoing HNC treatment. …

18 years of age All Phase N/A
s shun Lu

A Phase Ⅰb Study on Autologous GC101 TIL Injection for the Treatment of NSCLC

20 participants are expected to be enrolled for the Phase Ib clinical trial,this trail is expected to be finished in 36 months.

18 - 70 years of age All Phase 1
E Erica Heaton

The Seven Trial: Exploiting the Unfolded Protein Response

The goal of this investigator initiated interventional study is to improve the response to the anticancer treatments (chemotherapy) in people who have previously untreated metastatic pancreas cancer. The main question it aims to answer is: • Do new types of immune-based therapies, called botensilimab, and balstilimab, when given in combination …

18 years of age All Phase 1
H Haoxuan Wu, Doctor

Perioperative Immunotherapy for Resectable Limited-Stage SCLC

For limited-stage small cell lung cancer (SCLC), surgical treatment is recommended for patients with T1-2N0M0 (I-IIA) by guidelines. However, whether perioperative immunotherapy extends radical surgery to stage IIB-IIIB patients with improved survival remains elusive. This is a phase II, single-arm study to evaluate the efficacy and safety of neoadjuvant Tislelizumab …

18 - 75 years of age All Phase 2
M Matthias F Scriba, FCS (SA)

Evaluating Acid Reflux After Oesophageal Stenting Using Anti-reflux Stents

Incurable oesophageal cancer remains a global problem and in South Africa the vast majority of patients with oesophageal cancer have advanced disease at first presentation and are not curable. Likely the most distressing symptom of advanced cancer in the oesophagus is dysphagia, which is the inability to swallow solids and …

18 years of age All Phase N/A

PACED-digitized Support During Adjuvant Endocrine Therapy

The research team want to investigate whether digital support, an app under preventive hormonal breast cancer treatment can lead to less late side effects, better quality of life and increased adherence to treatment.

18 years of age Female Phase N/A
K Kyeongin Cha, PhDc

VR-based Intervention for Cognitive Restoration

The aim of this study is to test the efficacy of a nature-based cognitive intervention to restore cognitive function among women treated for breast cancer.

19 - 64 years of age Female Phase N/A

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