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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,447 clinical trials

Developing ctDNA Guided Adjuvant Therapy for Gastrooesophageal Cancer

Multicentre, single arm, open label UK phase II trial to assess the efficacy of trastuzumab deruxtecan in reducing micrometastatic disease burden in HER2 positive GOA patients who are ctDNA positive after chemotherapy and surgery. 25 patients will be recruited from approximately 15 NHS secondary care sites.

18 years of age All Phase 2

Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

The overall objective of this study is to develop a novel couple-based mindfulness intervention aimed at reducing distress in patients with metastatic colorectal cancer (mCRC) and their partners.

18 - 85 years of age All Phase N/A
C Carol Kwong, RN

Focal Radiotherapy for Previously Treated Prostate Cancer Patients

To examine the feasibility, safety and toxicity of focal stereotactic radiation treatment (SBRT) for locally recurrent prostate cancer.

18 years of age Male Phase N/A
C Clinical Trial Referral Office

Social Determinants of Health in Hepatobiliary Cancer Patients

This study evaluates barriers to receiving care and risks associated with developing cancer among patients diagnosed with hepatobiliary cancer.

18 years of age All Phase N/A
L Laura Cedrone

SBRT in Early Breast Cancer in Elderly Women

Surgical treatment represents the standard of local therapy in patients with early breast cancer, however in women over75, the comorbidities related to aging reduce the possibility of candidates for surgical treatment. In the United Kingdom it is estimated that over 40% of elderly women do not receive surgery for their …

75 years of age Female Phase N/A
C Chenyang Wang, MD

Hypophysectomy by Stereotactic Radiosurgery for Cancer-Related Pain

To learn if hypophysectomy (treatment of the pituitary gland) using a type of radiation treatment called stereotactic radiosurgery (SRS) can help to relieve cancer-related pain.

18 years of age All Phase 1
L Lone Volmer, MD

Mediterranean Diet and Inequality in Early Breast Cancer

Social determinants such as education, income, marital status, and social networks play a crucial role in cancer outcomes, including breast cancer. One potential influencing factor is diet, and the Mediterranean diet has been shown to benefit both the health and the microbiome. This raises the question: Does adherence to the …

18 years of age All Phase 2
J Jamie Walters

Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

This is a Phase 1/2, first-in-human, open-label, dose-escalating and expansion trial designed to assess the safety and efficacy of VNX-202 in patients with HER2 positive cancers.

18 years of age All Phase 1/2
J Joshua Meyer, MD

Adaptive Radiation for Locally Advanced Unresectable Pancreatic Cancer

The goal of this clinical trial is to learn if Adaptive Radiation Therapy (ART) is safe and effective in treating patients with locally advanced pancreatic cancer. The main questions the study aims to answer are: Can ART improve how well radiation therapy targets the most aggressive cancer cells, while protecting …

18 years of age All Phase N/A

Zolbetuximab Claudin18.2 Positive, HER2 Negative, Advanced Gastric Cancer

Treatment effectiveness in the real world Adverse effects Tissue samples collected (multiplex IHC to assess PD-L1 expression, MMR gene status, and Claudin18.2) Blood samples collected (ctDNA, scRNAseq, or immune cell profiling)

19 years of age All Phase N/A

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