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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,180 clinical trials
D David G Mutch, M.D.

Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

The purpose of this study is to determine the recommended Phase 2 dose of zanzalintinib when given in combination with paclitaxel in patients with recurrent high-grade uterine cancer. Other objectives include overall safety and tolerability as well as rates of response.

18 years of age Female Phase 1
Z Zhimin Shao, M.D.

Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer

This is a prospective, open-label, multicenter, phase II platform trial. The purpose of this study is to test the safety and effectiveness of the antibody-conjugated drugs (ADCs) in patients with advanced breast cancer who had previously used antibody-conjugated drugs.

18 years of age All Phase 2
T Ting Zhang, Prof.

Assessing Combined SBRT in Breast Cancer Non-Responders to Neoadjuvant Chemotherapy

The goal of this clinical trial is to assess whether the addition of preoperative stereotactic body radiation therapy (SBRT) can improve pathological complete response (pCR) rates and safety in breast cancer patients who do not respond to initial neoadjuvant chemotherapy. The main questions it aims to answer are: Can the …

18 - 75 years of age Female Phase 1/2
J Jeremy McGuire, PhD

Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer

To determine the feasibility of an 8-week fucoidan supplement intervention for patients with fatigue post-cancer treatment and assess changes in fatigue, frailty, and inflammation.

18 years of age All Phase 2
R Rachel Glicksman, MD

Stereotactic Body Radiotherapy or Standard of Care for Prostate Oligoprogressive Cancer

This is a single centre, interventional, randomized Phase II, two-arm prospective trial investigating if Stereotactic Body Radiotherapy (SBRT) to all sites of Oligopressive (OP) disease while remaining on current Systemic Therapy (ST) will improve biochemical control compared to Standard of Care (SoC) (which involves a change in ST) for patients …

18 - 100 years of age Male Phase 2
L Lauren Chang Sen, MD

3D Printed Breast Models in the Surgical Management of Breast Cancer

To learn if providing a 3-D printed model of the breast can help breast cancer patients make decisions related to their care. During this study, some study participants will receive the 3-D printed model and some study participants will receive traditional breast imaging scans to learn if the 3-D printed …

18 years of age All Phase N/A
X Xiangdong Cheng, Doctor

Study of IBI363 in Patients with Advanced First-line Gastric Cancer

This is a phase 1b study designed to evaluate the safety, tolerability and efficacy of IBI363 in combination with oxaliplatin and capecitabine (XELOX) in first-line treatment of unresectable advanced or metastatic gastric and gastroesophageal junction adenocarcinoma.

18 - 75 years of age All Phase 1
S Sine Jacobsen

Vaginal CO2 Laser Therapy for Genitourinary Syndrome in Breast Cancer Survivors

This project will be based on three studies over a period on three years. The first study is a dose response study that includes 30 breast cancer survivors. They will receive a total of 5 laser treatments with 4-6 weeks intervals The second study is a double-blind randomized controlled trial, …

18 - 100 years of age Female Phase N/A
Q Qingyuan Zhang, Ph.D

TQB2930 Injection for the Treatment of HER2-positive Advanced Breast Cancer

TQB2930 is a HER2 bispecific antibody drug. This study aims to evaluate the efficacy and safety of TQB2930 combined with investigator's choice of chemotherapy versus trastuzumab combined with investigator's choice of chemotherapy in subjects with HER2-positive advanced breast cancer who have received at least two prior lines of anti-HER2 therapy …

18 - 75 years of age All Phase 3

Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver Cancer

Treatment of intrahepatic cholangiocarcinoma (ICC) remains difficult. Many patients have unresectable tumors, and survival after resection was only slightly improved with the use of adjuvant capecitabine. One of the major prognostic factors is the resection margin, patients with invaded (R1) or narrow (<5mm) margins having a higher risk of recurrence. …

18 years of age All Phase 2

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