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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,180 clinical trials
M Maria Planck, MD,PhD

EGFR-mutated Lung Cancer in Randomized Investigator-Initiated Study

The purpose of this study is to evaluate the optimal sequence of EGFR-inhibitors in lung cancer patients with EGFR-positive tumors not amenable for curative treatment. Life quality, adverse effects and tumor response will be evaluated and analyses of obtained blood and tumor samples will be performed to identify molecular profiles …

18 years of age All Phase 3
M Monica Iorfida, MD

fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases

The aim of this study is to understand whether DWB-MRI (Diffusion Whole Body-Magnetic Resonance Imaging) is useful for early detection of locoregional or distant recurrence and whether early diagnosis influences the prognosis in high-risk populations thanks to the possibility of being able to use a more effective treatment. The primary …

18 - 75 years of age All Phase N/A

Adding IL-2 to Tebentafusp to Eradicate Cancer Progression

A recent clinical trial found that after 36 months, patients taking tebentafusp had a median survival of 21.6 months, compared to 16.9 months for those in the control group. Since recruitment for tebentafusp in metastatic uveal melanoma (mUM) has ended, a new trial is starting to test whether adding IL-2 …

18 years of age All Phase 1/2
M Mara M Mara Mantiero, MD

Akynzeo as Antiemetic Treatment in Patients With Endometrial Cancer

The clinical trial concerns the use of an innovative "anti-emetic" drug (that is, anti-vomiting and nausea) in subjects affected by endometrial cancer. It is addressed to patients who have never received chemotherapy before and are about to start a treatment with platinum and taxanes with or without immunotherapy for endometrial …

18 years of age Female Phase 4
G Gabriele Capurso, PhD

Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.

This will a be an open label, multicentre, randomized, controlled study in patients with unresectable pancreatic cancer, locally advanced or metastatic, with significant weight loss, and the tumour located in the head of the pancreas associated with dilated main pancreatic duct. Pancreatic Exocrine Replacement Therapy (PERT) in these patients will …

18 years of age All Phase 4
W Wan-Lin Zhan, Dr.

Airwave Compression Therapy to Prevent Breast Cancer-related Lymphedema

This study aims to explore the effectiveness of early intervention of airwave compression therapy to prevent the occurrence of postoperative breast cancer-related lymphedema(BCRL).

18 - 70 years of age Female Phase N/A
Y Yong Bae Kim

Preoperative Partial Breast Irradiation in Early-Stage Breast Cancer

In the management of early breast cancer patients, postoperative radiotherapy following breast-conserving surgery has been established as the standard treatment. Over the past two decades, significant changes have occurred in radiotherapy for breast cancer, encompassing dose fractionation methods, radiotherapy techniques, and delineation of the radiation field. Hypofractionated radiotherapy has been …

45 years of age Female Phase 2
S STEP-Together Coordinator

Sleep Treatment Education Program for Cancer Survivors: STEP-Together

This single-arm research study of off-treatment cancer survivors with self-reported symptoms of insomnia will test the Sleep Treatment Education Program Together (STEP-Together) intervention which is delivered as a synchronous group session by videoconference.

18 - 89 years of age All Phase N/A
F Franny Jongbloed, MD/PhD

Dietary Restriction to Prevent Cardiotoxicity in Breast Cancer Patients

The goal of this clinical trial is to compare a dietary intervention with a regular diet in patients with early breast cancer undergoing anthracycline based chemotherapy. The main question it aims to answer is: What are the effects of a short-term diet with 30% caloric and 70% protein restriction (PCR) …

18 - 75 years of age Female Phase N/A
R Rossana Ingargiola

Effect of Prehabilitation on Head and Neck Cancer Patients

The primary aim of the study is to investigate the feasibility of a prehabilitation program, which consists of a set of strategies including physical activity, nutritional support, and psychological counseling, carried out before and during cancer treatment for patients affected by head and neck tumors. About 4 weeks before surgery …

18 years of age All Phase N/A

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