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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,180 clinical trials
C Clinical Trial Referral Office

A Study of FRaDCs for Ovarian Cancer

The purpose of this study is to determine the response rate to the combination of folate receptor alpha dendritic cells (FRaDCs) plus pembrolizumab in patients with advanced ovarian, fallopian tube, or primary peritoneal cancer. Vaccines made from a person's peptide treated white blood cells may help the body build an …

18 years of age Female Phase 1/2
M Meghan Shea, MD

Dostarlimab and Cobolimab in Advanced Cervical Cancer

This research is being done to determine how effective dostarlimab in combination with cobolimab is in metastatic or recurrent cervical cancer.

18 years of age Female Phase 2
A Alicia Roy

Repositioning Immunotherapy in VetArans With Lung Cancer

This study is a multicenter Phase II single arm trial to assess the safety and efficacy of chemotherapy and immunotherapy followed by radiotherapy in patients with unresectable Stage III NSCLC.

18 years of age All Phase 2

Proton Therapy for Locally Advanced Cervical Cancer

The purpose of this protocol is to determine toxicity and efficacy of proton therapy in combination with standard concomitant platinum-based chemotherapy and standard image-guided adaptive brachytherapy (IGABT) in patients with locally advanced cervical cancer (LACC). The over-all aim is to maintain a high disease control and at the same time …

18 - 99 years of age Female Phase 2

Basket Study for Oligo-metastatic Breast Cancer

The study will include patients with HER2-positive breast cancer and 1- 3 distant metastatic lesions, all amenable for curative intervention. Patients will be stratified by prior therapy and ER expression. In the initial baskets patients with be treated with trastuzumab-deruxtecan. Patients are treated with T-DXd 5.4mg/kg on a three weekly …

18 years of age All Phase 2
J Juergen Debus, Prof. Dr. Dr.

Predicting Esophageal Cancer Borders Using PET-Imaging

The study examines the diagnostic precision of endosonography, mpMRI and PET/CT in defining tumor boundaries and tumor spread before and after neoadjuvant therapy and definitive surgery.

18 years of age All Phase 2
A Agathi Karakosta

Opioid-free Anaesthesia in Breast Cancer Surgery

Background Various analgesic modalities are adopted for perioperative analgesia in breast cancer surgeries. Opioid-free and opioid-sparing techniques are gaining popularity due to the lack of opioid-dependent undesirable effects, including respiratory depression, urinary retention, nausea and vomiting, constipation, itching, opioid-induced hyperalgesia, tolerance, addiction, and immune system disorders. The goal of this …

18 - 99 years of age Female Phase N/A
H Heather J Leach, PhD

Sustaining Physical Activity After Cancer Exercise Sessions

The goal of this clinical trial is to develop and test an adaptive physical activity (PA) maintenance intervention for cancer survivors, after participating in a community-based exercise oncology program. The main questions it aims to answer are: Aim 1: Examine the feasibility and acceptability of the intervention among cancer survivors …

18 years of age All Phase N/A
E Ebru Calik Kutukcu, PhD

Arterial Stiffness in Individuals With Breast Cancer

The aim of this study was to evaluate vascular toxicity induced by anthracyclines and other anticancer drugs and to measure arterial stiffness in women with breast cancer and, in addition, to evaluate the acute and chronic arterial stiffness responses of upper extremity aerobic exercise training.

40 - 69 years of age Female Phase N/A

Exercise and Nutrition Intervention in Ovarian Cancer

The objective of this multicenter randomized controlled trial is to compare a 6-month exercise and nutrition intervention (intervention group, IG) aimed at maintaining or improving physical functioning and quality of life with usual care (control group, CG) in ovarian cancer patients. The main question it aims to answer is: • …

18 years of age Female Phase N/A

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