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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,180 clinical trials
Q Qing Zhou, Doctor

Clinical Trial of TQB3002 in Patients With Advanced Cancers

This is a Phase I study to evaluate the safety, tolerability, and efficacy of TQB3002 in subjects with advanced cancers

18 - 75 years of age All Phase 1
J Jordan Georg

CT-95 in Advanced Cancers Associated with Mesothelin Expression

This is a Phase 1 open-label, dose escalation study to evaluate the safety and efficacy of CT-95 (study drug), a humanized T cell engaging bispecific antibody targeting Mesothelin, in subjects with advanced solid tumors associated with Mesothelin expression.

18 years of age All Phase 1
J Juliette THARIAT, Prof

Flap Sparing in Postoperative Radiotherapy of Oral Cavity Cancers

Patients with oral cavity cancer treated by reconstructive surgery with a flap. Patients will be treated in the study for : Experimental arm: Post-operative radiotherapy with flap sparing Control arm: Standard post-operative radiotherapy without flap sparing (current practice) Radiotherapy by IMRT using photons or proton therapy (IMPT)

18 years of age All Phase 3
L Lisa Barroilhet, MD

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

This phase I trial tests the safety, side effects, and best dose of RG1-virus-like particle (VLP) in preventing human papillomavirus (HPV)-related cancers in women. RG1-VLP is a vaccine that aims to protect against rare HPV types not targeted by currently approved HPV vaccines. HPV is a common sexually-transmitted infection that …

18 - 60 years of age Female Phase 1
K Katie Gatwood, PharmD

Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence

The objective of this study is to improve medication, symptom, and disease management of patients with hematological malignancies and multiple chronic conditions (2 or more conditions in addition to cancer) through care coordination between pharmacists working in oncology practices and those working in primary care or community practices (Pharmacists Coordinated …

18 years of age All Phase N/A
M Manoela D Martins, PhD

Comparison of Prophylactic Photobiomodulation Protocols in Chemoinduced Oral Mucositis in Oncology Patients

Childhood cancers represent less than 1% of the malignant diseases diagnosed worldwide. Treatment modalities for childhood malignancies will differ depending on the diagnosis. The main treatments may include chemotherapy (QT), radiation therapy (RT), and surgery. The toxicity caused by QT and RT generates adverse effects in the mouth, among them …

1 - 18 years of age All Phase N/A
A Alayne D Yamada, PhD

Prehabilitation Plus ERAS Versus ERAS in Gynecologic Oncology: a Randomized Clinical Trial

Prospective, interventionist, controlled and randomized study to test the effectiveness of a multimodal prehabilitation protocol in patients who will undergo gynecological surgery.

18 - 80 years of age Female Phase 3

Study Investigating Intravesical HDAC Inhibition to Improve Response to Immuno-Oncology Agents

In this study, we aim to evaluate the safety and efficacy of neoadjuvant combination using intravesical romidepsin and durvalumab in cisplatin-ineligible patients with muscle invasive bladder cancer (MIBC).

18 years of age All Phase 1
N Natasha Frederick, MD, MPH

Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention

The overarching goal is to develop and demonstrate proof-of-concept of ReSPECT (Reproductive and Sexual Health Patient Education and Communication Tool), a multi-modal communication intervention to improve adolescent and young adult (AYA)- clinician sexual and reproductive health (SRH) communication in the outpatient oncology clinic setting.

15 - 25 years of age All Phase N/A
L Lauren Reed-Guy, MD

Evaluating a Bidirectional Priming Intervention for Goals-of-care Communication in Oncology

This pilot study will evaluate whether an intervention aimed at hospitalized patients with advanced lung and gastrointestinal cancers can help facilitate goals-of-care (GOC) communication with their oncologists after discharge. While GOC communication is a recommended component of routine oncology care, many patients with solid cancers do not have the opportunity …

18 years of age All Phase N/A

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