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respiratory-syncytial-virus-rsv-infection Clinical Trials

A listing of respiratory-syncytial-virus-rsv-infection medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 27 clinical trials
Z Zoe Gardener, BSc

The Impact of Age on Adaptive Immunity in Adults Infected With Respiratory Syncytial Virus

This study will for the first time systematically investigate the immune responses in an elderly cohort challenged with a well-defined RSV inoculum. With a global aging population and continuing difficulties in generating vaccines that can reliably induce protective immunity in the elderly, these data will indicate the targets at which …

18 - 75 years of age Both Phase N/A

A Study To Evaluate the Safety of XW001 Inhalation in Children With RSV

This is a randomized, double-blind, placebo-controlled Phase Ib/IIa study to evaluate the safety, tolerability, efficacy, pharmacokinetics, and immunogenicity of XW001 inhalation in children with RSV infection in China

1 - 24 years of age Both Phase 1/2
Z Zhen Qin

A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV

To evaluate the safety, efficacy, pharmacokinetic (PK) characteristics and antiviral activity of different doses of Deuterium Hydrobromide for suspension in the treatment of respiratory syncytial virus infection in infants.

1 - 24 years of age Both Phase 2

Study of a Respiratory Syncytial Virus/Human Metapneumovirus Vaccine Candidate

The purpose of this study is to assess the safety and immunogenicity of a single intramuscular (IM) injection of different doses of an respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) vaccine candidate, in adult participants aged 60 years and older. In addition, the study will evaluate the safety and …

60 - 100 years of age Both Phase 1/2
J Jan Biegus, MD, Ph. D.

Coordinated Vaccination Against RSV and Influenza in Patients With Chronic Heart Failure and Its Impact on Prognosis.

This prospective, single-centre, open-label, randomized study aims to determine whether coordinated care in administering protective vaccinations (against Respiratory Syncytial Virus (RSV) and influenza) impacts the prognosis of patients with chronic heart failure. The main question it aims to answer is: • Does coordinated care through vaccinations improve the prognosis of …

18 - 100 years of age Both Phase N/A
G Gerdien Tramper, MD, PhD

Towards Life-Long Healthy Lungs: A Multidisciplinary Follow-up Framework for Preterm Infants

Approximately 8% of all births occur between 30-36 weeks of gestation ('moderate-late' prematurity). Respiratory tract infections (RTI) and wheezing illnesses disproportionally affect preterm infants resulting in a 1.5-2 fold higher hospitalisation rate during the first years of life compared to term born children. Besides prematurity, several other postnatal modifiable influencing …

- 100 years of age Both Phase N/A
K Kristian Tonby, MD PhD

Antibiotic Therapy in Viral Airway Infections

Antimicrobial resistance is one of the most urgent health threats of our time, and Norwegian hospitals were required to reduce the use of broad-spectrum antibiotics with 30% by the end of 2020. In the current proposal, the investigators aim to assess the efficacy and safety of early discontinuation of antibiotic …

18 - 100 years of age Both Phase 4
J Josefin Sundh, MD

Treatment of Respiratory Complications Associated With COVID19,Influenza ,Metapneumovirus,RSV Infection Using ProTrans®

To investigate the safety and tolerance of a single infusion of ProTrans® in subjects with "severe" respiratory complications associated with pneumonia caused by COVID-19, Influenza A, Metapneumovirus or RSV infection.

18 - 100 years of age Both Phase 1

Prospective Surveillance of Respiratory Syncytial Virus Disease in Infants and Toddlers

The study is a multi-center, multi-national, prospective surveillance study in which the study participants will not receive a study vaccine but will provide a baseline blood sample and be followed for acute respiratory disease during 6 months. The 6-month follow-up will occur for the most part during the Respiratory Syncytial …

6 - 21 years of age Both Phase N/A
F Federico Martinón Torres, PhD, MD

Evaluation of the Effectiveness and Impact of Nirsevimab Administered as Routine Immunization

A longitudinal observational study based on routinely collected data on hospital and health care use for RSV infections will be undertaken. The Galician public health registries will be used for data collection including baseline information and follow-up data. Historical data will be retrieved for comparison purposes. The study aims to …

1 - 24 years of age Both Phase N/A

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