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dyslexia Clinical Trials

A listing of dyslexia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 19 clinical trials
M Maria Luisa Lorusso, Ph.D

Poly-unsaturated Fatty Acids and Developmental Dyslexia

Poly-unsaturated fatty acids (PUFAs) represent a component of lipids that covers a relevant role in human diet and biological functions such as provision of energy, functionality of cell membranes and tissue metabolism. Fatty acids carbon chains can be saturated (with no presence of double bonds) or unsaturated (with one or …

7 - 15 years of age All Phase N/A
D Deny Menghini

V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia

The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation (tDCS) over left hemispheric direct Lateral Geniculate Nucleus (LGN)-V5/MT pathway, cerebral areas usually disrupted in individuals with DD. …

8 - 13 years of age All Phase N/A
S Sara Mascheretti, PhD

Gene x Environment Interplay in Developmental Dyslexia Treatment: A Round-trip Translation Between Humans and Animal

Developmental dyslexia affects 7% of school-age children (Male:Female ratio of 1.5:1) and incurs disadvantages in education and occupation. Scientific progress concerning the etiology of developmental dyslexia evidenced the complex gene-environment interaction. The DCDC2-READ1 deletion associates with reading skills and affects the magnocellular-dorsal stream in humans and animals. DCDC2 modifies neural …

5 - 6 years of age All Phase N/A
K Katherine S. Aboud, PhD

Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults

The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and 2.) high-definition non-invasive brain network stimulation. This study will first establish the efficacy of a …

18 - 40 years of age All Phase N/A

Executive Function in Early Childhood

Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via executive functions (EF), have not been unpacked. This project will use a longitudinal …

4 - 9 years of age All Phase N/A
O Olga Boukrina, Ph.D.

Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits

The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment. This approach is expected to increase cerebral circulation and help to rebuild and …

18 - 85 years of age All Phase N/A
M Maria Luisa Lorusso, Ph.D

Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children

The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated. The platform hosts screening tests for the identification of the risk of Language and Learning Disorders in preschool and primary school children, respectively. The …

4 - 9 years of age All Phase N/A
M Malida Franzoi, MD

Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties

Previous research has shown the importance of font type, size and spacing to facilitate text reading in dyslexia. A special automatized procedure was designed to select the most favorable parameters for both text visualization and text-to-speech (TTS) conversion to be used by students with reading difficulties. The validation of its …

7 - 15 years of age All Phase N/A
M Melissa Miller, Ph.D.

The Role of Knowledge Retrieval in Inference-making

This project will (a) examine the relationship between knowledge retrieval and inferencing; (b) determine the effectiveness of an intervention that improves knowledge retrieval and inferencing among struggling readers; and (c) expand research opportunities for undergraduates. The research design uses 316 struggling readers in grades 4-6 of diverse backgrounds. The effects …

8 - 14 years of age All Phase N/A

Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 Years

Studies of dyslexia have shown altered oscillatory activity in the low gamma band (~25-35 Hz) in the left auditory cortex. Neural oscillations around 30 Hz constitute the basic sampling rate of speech, from which the ability to form specific phonemic categories on which reading learning is based is derived. An …

7 - 9 years of age All Phase N/A

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