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heart-valve-disease Clinical Trials

A listing of heart-valve-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 320 clinical trials

Milrinone on Right Ventricular Strain in Cardiac Surgery

The purpose of this study is to analyze the changes in right ventricular strain before and after milrinone administration in order to find out whether milrinone improves RV systolic performance in patients undergoing cardiac surgery.

20 years of age All Phase N/A

Functional and Quality of Life Improvement Following Transcatheter Heart Valve Implantation

The objective is to observe trends in patient characteristics and outcomes after aortic or mitral transcatheter heart valve replacement over time.

18 - 110 years of age All Phase N/A

Pacemaker Implantation Following Transcatheter Tricuspid Valve Replacement

Transcatheter tricuspid valve replacement (TTVR) is associated with a high risk of third-degree atrioventricular block (AVB). However, the optimal pacemaker management following TTVR remains unclear. This study aims to identify an optimal therapeutic approach for pacemaker implantation in patients undergoing TTVR.

years of age All Phase N/A
A Alexandru Patrascu, MD

Pforzheim Tricuspid Valve Registry - Outcomes of Percutaneous Tricuspid Valve Repair

The Pforzheim Tricuspid Valve Registry study is designed to confirm the safety and performance of the TriClip™ device in a contemporary real-world setting in critically ill patients. The observational trial is a prospective, single arm, open-label, single-center, post market registry.

18 years of age All Phase N/A
J Johannes Kirchner, MD

CT Prediction for Transcatheter Tricuspid Interventions

The aim of this study is to enhance the predictability of therapeutic success in transcatheter tricuspid valve intervention (TTVI) for patients with severe tricuspid regurgitation (TR). This will be achieved through automated analyses of pre-interventional computed tomography (CT) scans. Severe tricuspid regurgitation is associated with poor patient outcomes. In advanced …

18 years of age All Phase N/A
H Henryk Dreger, Prof. Dr. med.

Berlin Registry of Right Heart Interventions

The present study evaluates patients after interventional therapy of valvular diseases of the right heart. Follow-up examinations include medical history taking, laboratory measurements and an echo. The aim is to assess the different interventional therapies and their impact on patient's outcome.

18 - 120 years of age All Phase N/A

Biomarkers of Inflammation and Fibrosis in Conduction Disorders After TAVI

Prediction of conduction disorders (CDs) in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) is an important and complex process with a significant impact on patient outcomes. The goal of this observational prospective trial is to investigate the role of pre-procedural values of systemic biomarkers of …

18 years of age All Phase N/A
D Department

ChAracterization of Patients and Treatment OUtcomes in Severe Tricuspid Regurgitation

The goal of this observational study is to characterize the population of patients qualified for transcatheter tricuspid valve interventions (TTVI). It is expected to: Describe the profile of patients qualified for TTVI Establish the most common causes for disqualification from TTVI Evaluate the immediate and long-term efficacy of TTVI Evaluate …

18 years of age All Phase N/A

Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System

The objective of this study is to evaluate the 5-year outcomes of participants with degenerative mitral valve disease treated with the NeoChord Artificial Chordae System, Model DS1000 in a post-market setting.

18 years of age All Phase N/A
C Christine Quast, MD

Phenotyping Heterogeneity and Regionality of the Aorta

The aorta distributes cardiac stroke volume into the whole body through its finetuned conductance function, that is propagation and modulation of flow pattern. Physicomechanic properties of the aortic wall assure continuous and homogenous blood flow distribution to organs. The physicomechanic properties of the aortic wall are heterotopic: The collagen/elastin ratio …

18 years of age All Phase N/A

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