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heart-valve-disease Clinical Trials

A listing of heart-valve-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 328 clinical trials

Milrinone on Right Ventricular Strain in Cardiac Surgery

The purpose of this study is to analyze the changes in right ventricular strain before and after milrinone administration in order to find out whether milrinone improves RV systolic performance in patients undergoing cardiac surgery.

20 years of age All Phase N/A
D Duk Hyun Kang, MD, PhD

Lipoprotein(a) and Progression of Aortic Stenosis

This study is a prospective, observational, two arm parallel group, clinical study involving patients with measurements of Lp(a) and mild to moderate aortic stenosis. A total of 1381 patients underwent measurement of Lp(a) and had a diagnosis of mild to moderate, degenerative aortic stenosis between 2001 and 2020 in Asan …

years of age All Phase N/A

Functional and Quality of Life Improvement Following Transcatheter Heart Valve Implantation

The objective is to observe trends in patient characteristics and outcomes after aortic or mitral transcatheter heart valve replacement over time.

18 - 110 years of age All Phase N/A
T Thomas Treibel, MBBS PhD

Aortic Stenosis and Cardiac Amyloidosis

The dual pathology of aortic stenosis (AS) and cardiac amyloidosis (CA) is increasingly recognized. Even tough efforts have been undertaken to bring cohorts together, the largest cohort of AS-ATTR to date is <50 patients. It is the aim of the present international, multi-center registry to collect ~300 patients with AS-CA …

18 years of age All Phase N/A

Pacemaker Implantation Following Transcatheter Tricuspid Valve Replacement

Transcatheter tricuspid valve replacement (TTVR) is associated with a high risk of third-degree atrioventricular block (AVB). However, the optimal pacemaker management following TTVR remains unclear. This study aims to identify an optimal therapeutic approach for pacemaker implantation in patients undergoing TTVR.

years of age All Phase N/A
A Alexandru Patrascu, MD

Pforzheim Tricuspid Valve Registry - Outcomes of Percutaneous Tricuspid Valve Repair

The Pforzheim Tricuspid Valve Registry study is designed to confirm the safety and performance of the TriClip™ device in a contemporary real-world setting in critically ill patients. The observational trial is a prospective, single arm, open-label, single-center, post market registry.

18 years of age All Phase N/A

Reliability of Artificial Intelligence (AI)-Augmented Point-of-care Cardiac Ultrasound in the Hands of Internists

The study aim is to test the diagnostic performance of internists interpreting echo images aided by the AISAP CARDIO V0.7 diagnostic support system. Ground truth will be established by an interpretation by cardiologists specialized in echo, of the same POCUS images (acquired by the internist \ sonographer ). Up to …

years of age All Phase N/A
J Johannes Kirchner, MD

CT Prediction for Transcatheter Tricuspid Interventions

The aim of this study is to enhance the predictability of therapeutic success in transcatheter tricuspid valve intervention (TTVI) for patients with severe tricuspid regurgitation (TR). This will be achieved through automated analyses of pre-interventional computed tomography (CT) scans. Severe tricuspid regurgitation is associated with poor patient outcomes. In advanced …

18 years of age All Phase N/A
H Henryk Dreger, Prof. Dr. med.

Berlin Registry of Right Heart Interventions

The present study evaluates patients after interventional therapy of valvular diseases of the right heart. Follow-up examinations include medical history taking, laboratory measurements and an echo. The aim is to assess the different interventional therapies and their impact on patient's outcome.

18 - 120 years of age All Phase N/A
P Peter Raivio, MD, PhD

Spectroscopic Assessment of Intramyocardial Oxygen Saturation During Open-Heart Surgery

The goal of this observational study is to test in the safety and performance of intraoperative myocardial spectroscopic measurement in open-heart surgery patients The main questions it aims to answer are: The Devices can record myocardial spectrometric data for analysis, and How these measures correlate with the occurring events, procedures, …

18 - 90 years of age All Phase N/A

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