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urethral-strictures Clinical Trials

A listing of urethral-strictures medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 11 clinical trials
M Malakah Mohamed, secretary

Anatomical and Functional Outcome of PSG Vs BMG for Urethral Substitution in Long Segment Anterior Urethral Strictures

This study aims to compare the penile skin graft and buccal mucosal graft for substitution of long anterior urethral strictures using one-sided dorsal perineal approach.

5 - 100 years of age Male Phase N/A
T Teng Aik Ong, Prof

Bioengineered Collagen Implant for Urethral Stricture Repair

The field of research for this study is tissue engineering and the utilization of a bioengineered collagen implant as a substitute biomaterial for conventional buccal mucosa in substitution urethroplasty of distal urethral strictures.

18 - 100 years of age Male Phase N/A
W Wesley Verla

Multi-stage Urethroplasty With Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second Stage

The principal aim of this pilot study is to directly compare both approaches and analyze the failure rate after one year of follow-up. These data will serve as the basis to design a larger phase II or III trial in the future with failure rate as the primary end-point. Other …

18 - 100 years of age Male Phase N/A
H Holly Baril

Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters

Single-arm, prospective study assessing semen quality after treatment with the Optilume Urethral DCB in men between 22 and 65 years of age.

22 - 65 years of age Male Phase 4
N Nicolaas Lumen

DoVe Trial: Dorsal Onlay Versus Ventral Onlay in Isolated Bulbar Urethral Strictures

For bulbar urethral strictures, it remains unclear whether ventral onlay graft urethroplasty is non-inferior to dorsal onlay graft urethroplasty in terms of patency rates.

18 - 100 years of age Male Phase N/A
G GILLES KARSENTY

Safety and Potential Effect of Innovative Treatment by Adjuvant Injection of Stromal Vascular Fraction From Autologous Adipose Tissue of URethral Stenosis With Endoscopic Urethrotomy

SURF is a randomised controlled, parallel group, single blind phase II study designed to assess the safety and potential efficacy of an innovative therapeutic strategy for urethral stenosis based on adjuvant injection of autologous Adipose-Derived Stromal Vascular Fraction of Adipose Tissue (ADSVF) during endoscopic urethrotomy (standard care).

18 - 85 years of age Male Phase 2
M Mohamed F Salman, MD

Role of Paclitaxel in Stricture Urethra

Stricture urethra is a common disease and has various causing factors. The most common performed procedure is direct visual internal urethrotomy (DVIU), but unfortunately has a high recurrence rates. Multiple trial were performed to improve the outcomes of DVIU. Various intralesional injections were used. in this trial we will evaluate …

18 - 100 years of age Male Phase N/A
J Jianwei Wang

Treatment of Urethral Stricture With Urethral Drug Ball

To evaluate the safety and efficacy of urethral drug balloon catheter in the treatment of urethral stricture.

18 - 85 years of age Male Phase N/A
L Lindsay A Hampson, MD

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no established best practice for peri-operative pain management in this …

18 - 100 years of age Male Phase 3
W Wesley Verla

9000 URETHRA STUDY: a Study About Urethroplasty for Urethral Stricture Disease

It has been demonstrated that urethroplasty should be considered the gold standard treatment for urethral stricture disease as it yields higher long-term success rates than endoscopic treatment options such as direct vision internal urethrotomy (DVIU) or dilation. Many data about these procedures exist, although most of the publications about urethroplasty …

6 - 100 years of age Both Phase N/A

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