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Hemophilia Clinical Trials

A listing of Hemophilia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 94 clinical trials
S Susan Shapiro, MD PhD

The CACHE Study: Coronary Artery Care in HaEmophilia

The investigators will use state-of-the-art imaging to look at heart disease in people with haemophilia. Haemophilia is an inherited disorder in which blood does not clot properly because of lack of a key 'glue' blood component (chemicals known as factor VIII or IX). People with haemophilia are 40% less likely …

45 - 120 years of age Male Phase N/A
Y Yeu-Chin chen

A Study on the Bone-health Effectiveness of Applying Recombinant Factor VIII Fc (rFVIIIFc) to Patients With Hemophilia A (Prototype A)

Study Objectives* Provide a systematic evaluation of the treatment outcomes in patients with hemophilia A Emphasize the importance and clinical benefits of rFVIII-Fc in joint and bone health. Compare the clinical outcomes from 1 year before and after switching to EHL. Exploratory: Identify biomarkers that could provide more useful and …

years of age Male Phase N/A
P Paul Batty, MBBS MRCP

Liver Biopsy In Haemophilia Gene Therapy

To perform a liver biopsy in haemophilia A and B patients stably expressing human FVIII/FIX for a period of at least 6 months following AAV mediated gene transfer. This is to obtain tissue for analysis, to understand if FIX/FVIII transgenic protein expression is mediated by AAV proviral DNA that is …

18 - 80 years of age Male Phase N/A

An Observational Cohort Study to Characterize the Effectiveness and Safety of HEMGENIX® in Patients With Hemophilia B

This observational, post-authorization, long-term follow-up study aims to investigate the short and long-term effectiveness and safety of HEMGENIX in patients with hemophilia B. The study will also include a cohort of patients with hemophilia B treated with FIX prophylaxis to enable interpretation of relevant efficacy and safety findings of HEMGENIX.

18 years of age All Phase N/A

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