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sprains Clinical Trials

A listing of sprains medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 66 clinical trials
G Glen P Kenny, PhD

Impact of Indoor Overheating on Physiological Strain in Children

Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children. Compared with adults, children are more susceptible to heat related illness due to less efficient thermoregulatory systems and difficulty recognizing early signs of heat stress. In addition, prolonged heat …

10 - 15 years of age All Phase N/A

Effect of a Multi-strain Probiotic on Recurrent Vulvovaginal Candidiasis

This study evaluates the effect of a multi-strain probiotic on the risk of recurrence and severity of symptoms in females with recurrent vulvovaginal candidiasis (R-VVC).

18 - 50 years of age Female Phase N/A
V Victoria Parker, MBBS

Dose, Safety, and Pathogenicity of a New Influenza B Strain

This is an exploratory study of an influenza B challenge strain to determine the optimum infectious titer of challenge agent in healthy participants 18 to 55 years of age.

18 - 55 years of age All Phase 2
E Erik Wikstrom, PhD

Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation

The purpose of this project is to compare a novel sensorimotor ankle rehabilitation training (SMART) protocol for Lateral ankle sprains (LASs) against a standard of care (SOC) protocol to determine if it is more successful at producing successful one-year outcomes and lower rates of re-injury and improved health. This will …

18 - 44 years of age All Phase N/A

Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability

The goal of this randomized clinical controlled trial is examine the effects of gait training with auditory biofeedback (AudFB) on gait biomechanics, clinical measures of ankle joint health, and patient-centered outcomes. The following specific aims will achieve this objective: Specific Aim 1: Determine if a 6-week gait training with AudFB …

18 - 45 years of age All Phase N/A
N Naveen Poonai, MD

A Mobile Recovery Guidance App for Children and Young Adults With Acute Ankle Inversion Injuries

Ankle sprains are the most common musculoskeletal complaint of children presenting to the emergency department (ED). Healing can often be protracted, leading to prolonged pain, missed school and work, and delayed return to a normal activity level. Smartphone apps have been shown to be associated with greater caregiver knowledge and …

12 - 30 years of age All Phase N/A

Effect of Eccentric Streching vs IASTM of Gastrocnemius and Soleus Muscles in Athletes With Ankle Sprain

The primary objective within the current study is to compare the acute and chronic effects of eccentric training and IASTM on the dorsiflexion ROM. To reduce the risk of Achilles tendinopathy, stretching and eccentric (lengthening) exercises are postulated to improve ankle dorsiflexion. An eccentric exercise lengthens an active muscle while …

18 - 50 years of age All Phase N/A
H Hira Shaukat, TDPT

Strain Counterstrain Technique and Graston Technqiue on Quadratus Lumborum Trigger Points

Poor body mechanics and posture affects body positioning and stresses quadratus lumborum muscle which ultimately leads to myofascial trigger points in muscle. This study aims to compare the effects of Strain counterstrain technique and Graston technique on trigger points of quadratus lumborum in nonspecific low back patients. This study will …

20 - 45 years of age All Phase N/A
K Krzysztof Durkalec-Michalski, PhD

Effect of a Short-term Multi-strain Probiotic Supplementation in Endurance Athletes

The aim of this project is to evaluate and identify the effect of a short-term 2-week multi-strain probiotic (MPRO) supplementation on the exercise-associated gastrointestinal (GI) symptoms and perturbations in high level female athletes of the Polish national team during strictly controlled conditions of a training camp, based on recommendations for …

16 - 50 years of age Female Phase 2/3
A Ayca Yagcioglu, MSc

Spinal and Supraspinal Control in Chronic Ankle Instability

Ankle sprains are common sports injuries that often lead to chronic ankle instability (CAI). Patients with CAI experience deficits in neuromuscular control (NMC), including proprioception and strength. It is believed that damage to the ankle's ligament mechanoreceptors and the peroneal nerve after the initial ankle sprain can cause alterations in …

18 - 25 years of age All Phase N/A

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