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fecal-incontinence Clinical Trials

A listing of fecal-incontinence medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 33 clinical trials
J Jan Lehmann

Skeletal Muscle-derived Cell Implantation for Treatment of Fecal Incontinence

The objective of this study is the final assessment of clinical safety and efficacy of autologous autologous skeletal muscle derived cells for patients with urge fecal incontinence due to external anal sphincter dysfunction caused by its disruption and/or weakness.

18 - 100 years of age Both Phase 3

Efficacy of Antenatal Perineal Massage in Reducing Postpartum Morbidities

A randomized controlled trial was undertaken at Rajavithi Hospital, Bangkok, Thailand, encompassing 106 primigravidae within the period of December 2023 to June 2024. The intervention group underwent antepartum perineal massage, starting at the 34th - 35th week of gestation and extending until delivery, while the control group did not receive …

18 - 50 years of age Female Phase N/A
S Sam Treadway

Pelvipower for Faecal Incontinence

Faecal incontinence (FI) is a common condition which drastically reduces patient's quality of life and for which there are few effective treatments. The causes of FI are multiple and include disturbances in neuromuscular function (and structure) of the anal canal, rectum and pelvic floor. Treatment options include antidiarrheals, laxatives, biofeedback, …

18 - 100 years of age Female Phase N/A
E Eloy Espin Basany, MD

UCon Treatment of the Symptoms of Faecal Incontinence (FI)

UCon is a medical device for treatment of the symptoms of overactive bladder and fecal incontinence (FI). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature e.g., suppress undesired bladder/bowel activity to relieve the symptoms of the patient. This clinical investigation is designed …

18 - 100 years of age Both Phase N/A

Topical Vaginal Estrogen for Postpartum Obstetric Anal Sphincter Injury Recovery

Obstetric anal sphincter injuries (OASIS) cause significant morbidity and are well known risk factors for sexual dysfunction, urinary and anal incontinence. Postpartum and breastfeeding are relative hypoestrogenic states with risk factors for dyspareunia and vaginal atrophy. Estrogen deficiency results in changes in the vaginal epithelium and poor tissue quality which …

18 - 100 years of age Female Phase 4
M Mary-Clare Day, RN

Autologous Muscle Fiber Fragment Injections

To regenerate functional anal sphincter muscle using muscle fiber fragments that contain muscle precursor cells (MPCs)

18 - 100 years of age Both Phase N/A

Treatment of Fecal Incontinence and Functional Defecation Disorders Using Non-instrumental Biofeedback

Background. Rehabilitation and re-education using instrumental anorectal biofeedback are the main treatment of anorectal functional disorders producing incontinence and outlet obstructed defecation. These treatments imply intubation of patient and several sessions of treatment leading to high consumption of resources and costs. Hypothesis. A cognitive intervention based on original audiovisual programs …

18 - 75 years of age Both Phase N/A

Evaluation of the Efficacy and Safety of Autologous Fat Injection Into the Intersphincter Space in Fecal Incontinence: a Randomized, Placebo-controlled, Cross-over, Double-blind Trial

Fecal incontinence is frequent and has a significant impact on the quality of life of individuals. Its therapeutic management is based primarily on transit regulation and rehabilitation and secondarily on neuromodulation of the sacral roots. However, this strategy is insufficient in more than one patient out of three. The patient …

18 - 100 years of age Both Phase N/A

Iltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females with Obstetric Injury

This study evaluates the efficacy and safety of a single injection of iltamiocel (300 x 10^6 cells) compared to a placebo in the reduction of fecal incontinence episode frequency in adult female participants with chronic fecal incontinence and a history of obstetric anal sphincter injury. Half of the participants will …

18 - 100 years of age Female Phase 3
J Jihong Chen, MD PhD

Sacral Neuromodulation as Treatment for Fecal Incontinence

The objective of this study is to investigate if low level laser therapy will do more good than harm for patients with severe refractory fecal incontinence. It is a proof of concept study without a placebo arm.

6 - 80 years of age Both Phase N/A

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