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Prostate Cancer Clinical Trials

A listing of Prostate Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,098 clinical trials
H Harriet Eldredge-Hindy, MD

Stereotactic Ablative Radiation Therapy for Prostate Cancer

This single arm trial will investigate a novel way to plan and deliver SABR for prostate cancer. Prostate-directed SABR will be high-dose SABR (40 Gy in 5 fractions) with central sparing of the urethra and peripheral sparing of the rectum and pudendal arteries (SUPR-SABR). This study tests the hypothesis that …

18 years of age Male Phase N/A
G GENELYTICA

A Phase 2/3,PSMA-T4, Prostate Cancer

The objectives of this study are to evaluate the feasibility and safety of [99mTc]Tc-PSMA-T4 in the diagnosis and treatment planning of prostate cancer.

18 years of age Male Phase N/A
C Charlien Berghen, MD

Trial to Investigate the Benefit of Elective Para-Aortic Radiotherapy (PART) for pN1 Prostate Cancer

Prospective non-randomized phase 2 trial to study the efficacy of additional elective para-aortic RT (PART) in pN1 patients compared to those who were historically treated with adjuvant whole pelvic radiotherapy (WPRT) alone.

18 years of age Male Phase 2
N Natalie E Freeman, PhD

Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer

This study is being proposed to evaluate the use of moderate hypofractionated proton therapy in low and intermediate risk prostate cancer patients. Quality of life outcomes as well as gastrointestinal and genitourinary early and late toxicities will be analyzed and compared to conventional proton therapy regimens. It is thought that …

18 years of age Male Phase N/A

Phase II Study of Single-Dose Image-Guided Radiotherapy (SDRT) for Prostate Cancer

The present study evaluates clinical outcomes and treatment-related toxicity following definitive ultra-high single dose external beam radiotherapy delivered to patients with lowor intermediate-risk adenocarcinoma of the prostate. Modern computer-driven technology enables the implementation of ultra-high Single-Dose Image-Guided Radiotherapy (SD-IGRT) safely. Prostate cancer patients classified according to the current National Comprehensive …

18 years of age Male Phase N/A
S Site Public Contact

Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation

The purpose of this research is to gather information on the safety and effectiveness of combining focal prostate ablation therapy ((aka Focal Therapy, a surgical procedure) and androgen deprivation therapy (hormone therapy).

18 years of age Male Phase 2
P Pascale Juneau, MASc

Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy

Prostate cancer is the most common cancer in men and radical prostatectomy is the most frequent treatment for this disease. Unfortunately, approximately 40% of patients will develop recurrence after surgery, requiring additional salvage radiation. Salvage radiation after recurrence is successful in less than half of these men and most of …

18 years of age Male Phase 3

Efficacy and Safety of Darolutamide Combined With ADT in High-risk/Very High-risk Localized Prostate Cancer

This trial aims to evaluate the efficacy and safety of neoadjuvant therapy with Darolutamide combined with Androgen-Deprivation Therapy in High-risk/Very high-risk localized prostate cancer. This trial is A prospective, single-arm, multicenter clinical trial. Treatment cycle is 24 weeks,

18 - 75 years of age Male Phase 2
L Lorna Bower

Hypofractionated Expedited Radiotherapy for Men With localisEd proState Cancer

The purpose of this research is to investigate whether stereotactic body radiotherapy (SBRT), precise X-ray treatment, is best given in five treatments (also called fractions) over 10 days or in two treatments over 8 days. SBRT is an accurate way to deliver a high dose of radiotherapy to the prostate …

18 years of age Male Phase N/A
M Michael Baumann, Prof.

Preference-based Comparative Study on Definitive Radiotherapy of Prostate Cancer With Protons

ProtoChoice-P is a prospective multicenter trial to evaluate proton therapy in patients suffering from prostate cancer. Primary aim of the study is a decrease of moderate or severe genito-urinary or intestinal side effects (Common Terminology Criteria for Adverse Events (CTCAE) 4.0 grade 2 or higher) by the use of proton …

18 years of age Male Phase N/A

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