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miscarriage Clinical Trials

A listing of miscarriage medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 25 clinical trials
L Lisa Lashley, MD, PhD, MsC

Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages

Recurrent miscarriages (RM) affects 3% of all fertile couples, but remains unexplained in most cases, limiting therapeutic options. Possibly the maternal immune system plays a role in recurrent miscarriage. Prednisolone suppresses the immune system and might enable development of normal pregnancy. In this randomized controlled clinical trial the investigators will …

18 - 40 years of age Female Phase 4
N Ni-Chin Tsai, MD

Investigation and Diagnosis of the Chromosome Variation in Donated/Abandoned Blastocyst

Blastocysts derived from patients seeking infertility treatment were generated by in vitro fertilization and embryo culture as previously described, and were evaluated using the Gardner system. As part of the embryo selection process, cells of TE biopsy were collected, and blastocysts were vitrified. The clinical TE biopsies were subjected to …

20 - 50 years of age Female Phase N/A
S Stacey Wong, BSc

Effect of Prednisolone Treatment on Uterine Natural Killer Cells

This study aims to investigate the role of uNK cells and the association with prednisolone.

18 - 40 years of age Female Phase 3
J Jhuma Biswas

Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages

Prospective interventional study where participants with non-viable pregnancy at 1st trimester will be randomized into two arms, one group will receive conventional treatment with oral mifepristone followed by misoprostol vaginally and another group will receive letrozole for three consecutive days followed by misoprostol vaginally in an attempt to terminate the …

18 - 40 years of age Female Phase 3
M Martha DURAES, MD

Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic Retention

Introduction: Incomplete early miscarriage is defined as early miscarriage with persistent intrauterine material on ultrasound. Intrauterine retention of trophoblastic debris is not an uncommon phenomenon. These retentions may initially be asymptomatic but are often responsible for persistent metrorrhagia and endometritis. This symptomatology often accentuates the psychological distress of patients mourning …

18 - 42 years of age Female Phase N/A
M Mónica Cameirão, PhD

Virtual Reality for Coping With Involuntary Early Pregnancy Loss

This study aims to provide psychological support to women that experienced an Early Pregnancy Loss (when the loss occurs until the 20 weeks of gestation) using an innovative Virtual Reality prototype and compare the presence and evolution of psychological distress symptoms pre and post-intervention. The main goals of this study …

18 - 100 years of age Female Phase N/A
D Dominic Stoop

The Use of High Concentration Hyaluronic Acid (HA) Transfer Medium in Repeated Implantation Failure (RIF) Patients

This is a pilot study with the aim to investigate the beneficial effect of bicarbonate buffered medium containing hyaluronan and recombinant human albumin (EmbryoGlue®, Vitrolife) in patients with documented repeated implantation failure on live birth per randomized subject as primary endpoint.

18 - 40 years of age Female Phase N/A
M Mohamed I Eid, Dr

Use of Warfarin After the First Trimester in Pregnant Women With APS

Evaluation of shifting to oral vitamin K antagonist after the first trimester instead of using low molecular weight heparin (LMWH) throughout pregnancy in pregnant women with antiphospholipid syndrome (APS)

20 - 38 years of age Female Phase 4
A Amandine Dernoncourt, DR

Immune Profile Analysis and Biomarker Identification in Women With Repeated Implantation Failure or Unexplained Recurrent Spontaneous Miscarriage

Implantation is a determining step in human reproduction which requires the transition from a pro-inflammatory state to an anti-inflammatory state allowing the implantation of a competent embryo within a receptive endometrium, and then the maternal immunotolerance towards the alloantigenic fetus. Repeat implantation failures (RIFs), that refers to the fail to …

18 - 39 years of age Female Phase N/A
R Rahana Abd Rahman

Gemeprost Versus Dinoprostone in First Trimester Miscarriages

Comparison between gemeprost and dinoprostone to evacuate first trimester miscarriages.

18 - 50 years of age Female Phase 2

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