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essential-tremor Clinical Trials

A listing of essential-tremor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 42 clinical trials

Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET)

The goal of this clinical study is to compare ulixacaltamide and placebo treatment in essential tremor. The main question it aims to answer is: • Is ulixacaltamide a safe and efficacious treatment for patients with essential tremor? Participants will be asked to participate in one of two clinical studies where …

18 - 85 years of age Both Phase 3

A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor

The primary purpose of this study is to evaluate the long-term safety and tolerability of SAGE-324 in participants with essential tremor (ET).

18 - 80 years of age Both Phase 2/3
K Kristina Simonyan, MD, PhD

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.

- 100 years of age Both Phase N/A
K Kristi Winterfeldt, MSHS

Upper Limb Tremor Reduction in Essential Tremor Patients

This study is designed to demonstrate the safety and tolerability of the Encora Therapeutics Tremor Mitigation Device in subjects with upper limb tremor caused by Essential Tremor.

22 - 80 years of age Both Phase N/A
E Edouard COURTIN, Dr

Electroclinical Correlates in Essential Tremor

Essential tremor (ET) is a neurological disorder that affects nearly 0.9% of the world's population. High-frequency Deep Brain Stimulation (DBS) of the ventral-intermediate nuclei of the thalamus (VIM) has been proven as an effective second-line treatment for severe forms of ET. The arrival on the market of the PERCEPT™ (new …

18 - 75 years of age Both Phase N/A

The Swedish Essential Tremor (SWEET) Trial

To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.

18 - 75 years of age Both Phase N/A
C Christian Iorio-Morin, MD, PhD

Bilateral Essential Tremor Treatment With Gamma Knife

Combined Phase II/III, multi-center, prospective, single-blinded trial. Ten (10) patients with essential tremor who previously underwent successful and uncomplicated GK thalamotomy for essential tremor will undergo a contralateral treatment. The incidence of side effects will be determined at 3 months postoperatively, graded per the CTCAE v5 and analyzed by a …

18 - 100 years of age Both Phase 2/3

Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor

The purpose of this study is to evaluate the efficacy and electrophysiology of repetitive transcranial magnetic stimulation in the treatment of essential tremor.

18 - 80 years of age Both Phase N/A
J Jing Wang, PhD

Coordinated Reset Deep Brain Stimulation for Essential Tremor

Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinated reset DBS (CR-DBS) which uses different patterns of stimulation at lower currents and can address the limitations of traditional DBS that uses continuous high amplitude, …

21 - 100 years of age Both Phase 1
M Mary Ann Barnett

3-D Tractography FUS Ablation for Essential Tremor

The investigators propose to advance Vim-FUSA (Ventral Intermediate Nucleus - Focused Ultrasound Ablation) with the support of 3-D tractography, a neuroimaging technique to visually represent nerve tracts within the brain. The investigators hypothesize that 3-D tractography Vim-FUSA will improve the Vim ablation compared to standard Vim-FUSA and prove safe and …

22 - 100 years of age Both Phase N/A

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