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arrhythmia Clinical Trials

A listing of arrhythmia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 572 clinical trials
W Winston WS Shing, MBBS

Pharmacokinetics of Apixaban in Peritoneal Dialysis

Atrial fibrillation (AF) is fairly prevalent in patients with end stage renal disease (ESRD) with the prevalence estimated to be 3.8 - 27%. While it is reported that patient with peritoneal dialysis (PD) has a lower incidence of AF as compared to patient with haemodialysis (HD), the risk is still …

18 - 80 years of age All Phase N/A
B Bob GS Abeln, MD

Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging

Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion …

18 years of age All Phase N/A
Y Yingjie Chu

Application Value of Whole-procedure Optimization for Catheter Ablation of Atrial Fibrillation

The success rate of single-procedure atrial arrhythmia-free survival particularly ranged from 40% to 66% in persistent AF ablation. However, The surgical Cox maze III procedure has been established to be an effective curative strategy for AF with an AF-free survival rate of more than 95%. The main reason is the …

18 - 80 years of age All Phase N/A
J Jarle Jortveit, PhD

Atrial Fibrillation Prior and Post Elective Cardioversion

Cardioversion from atrial fibrillation (AF) to sinus rhythm (SR) is performed primarily to improve patient symptoms. However, due to the intermittent nature of AF, patients may have converted to SR prior to elective cardioversion and the recurrence rate of AF after cardioversion can be high. The aims of this study …

18 years of age All Phase N/A
H Henri Gruwez, MD

Observational Study of Sinus Rhythm Mapping in Pulmonary Vein Isolation Naive Patients With Atrial Fibrillation

Atrial fibrillation (AF) initially starts in a paroxysmal form, which is mainly based on the presence of triggers. Progression of AF is accompanied by structural and electrical remodelling which can typically be described as a progressive change in electrophysiological properties of the myocardium caused by cardiovascular comorbidities and AF itself. …

18 years of age All Phase N/A
P Piotr Sobocinski Doliwa, M.D. Ph.D.

Progression of Atrial Fibrillation in the Young

The purpose of this study is to investigate the presence and magnitude of structural changes of the heart and their long-term development in young patients with atrial Fibrillation (AF), studied by echocardiographic measurements and plasma biomarkers and their association to AF burden, studied using long-term ECG

18 - 50 years of age All Phase N/A

Lifetech LAmbre™ Left Atrial Appendage Closure System Post-Market Registry

Single-center, single-arm, prospective, post-market study of LAmbre™ LAA Closure System. To evaluate immediate and long term procedural success of Lifetech LAmbre™ occluders in patients.

18 years of age All Phase N/A
T Toral Odedra

An Investigator-initiated Linked Study to OCEANIC-AF

Impaired endogenous fibrinolysis is a recently recognised risk factor for thrombotic events in patients with cardiovascular disease. Enhancing endogenous fibrinolysis in such individuals represents a way of reducing thrombosis risk. However, the optimal pharmacotherapy to enhance fibrinolysis is unclear. The aim of this study is to assess the effect of …

18 years of age All Phase N/A
K Kathleen Mills, BA

The Dynamics of Human Atrial Fibrillation

Atrial fibrillation (AF) is an enormous public health problem in the United States, affecting 2-5 million Americans and causing rapid heart beats, stroke, heart failure or death. In this project, the applicant will develop a novel framework to better understand human AF that builds on agreement between several concepts for …

22 - 80 years of age All Phase N/A

Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation

This is a prospective, case-control study that seeks to learn about the role of genetics in early onset atrial fibrillation (AF) and if genetic testing can be used to improve how the investigators treat atrial fibrillation. The study will enroll 225 participants. Eligible participants will have undergone sequencing for arrhythmia …

18 years of age All Phase N/A

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