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arrhythmia Clinical Trials

A listing of arrhythmia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 565 clinical trials
C Carlo de Asmundis, MD, PhD

Multicenter Registry of Atrial Fibrillation Ablation With Radiofrequency Balloon Catheter

All consecutive patients with paroxysmal or persistent atrial fibrillation undergoing pulmonary vein isolation with the radiofrequency balloon catheter (RFB) "Heliostar" (Biosense Webster) will be included in a multicenter observational registry. The aim of the study is to assess the safety and arrhythmic outcome of atrial fibrillation ablation with the RFB …

18 - 85 years of age All Phase N/A
P Pontawee Kaewcomdee, B.N.S

COhort of antithrOmbotic Use and cLinical Outcomes in Patients With Atrial Fibrillation (COOL-AF) Phase 2

Atrial fibrillation (AF) is a leading cause of cardiovascular mortality and morbidity. Asian patients with AF have a higher rate of major bleeding including intracranial hemorrhage (ICH) compared to non-Asians. Non-vitamin K antagonist oral anticoagulants (NOACs) are the safer drugs compared to warfarin due to a lower rate of ICH, …

18 - 100 years of age All Phase N/A
J Juan C Souto, MD, PhD

Real-life Clinical Outcomes of Direct Oral Anticoagulants (MACACOD)

MACACOD is a clinical record in the usual clinical practice of direct oral anticoagulants (dabigatran, rivaroxaban, apixaban and edoxaban). Design: single-center, observational, prospective, uncontrolled study of anticoagulated patients with any direct oral anticoagulant (DOAC) with atrial fibrillation or venous thromboembolism to determine the incidence of serious complications (thromboembolic or hemorrhagic) …

18 years of age All Phase N/A
D Daniel Engler, MSc.

Cohort Study for Atrial Fibrillation Risk Stratification

AFHRI is planned as a prospective, single-center cohort study in patients at high risk of AF.

18 - 85 years of age All Phase N/A

The Multicenter Cardiology Monitoring Platform Registry

The multicenter Cardiology Monitoring Platform registry (mCMP-registry) is a prospective observational registry including multi-omics (diagnostic) measurements performed as part of routine clinical care, bio-banking (optional), and yearly questionnaires (optional). It's objective is to optimize (early) diagnosis and risk-stratification of (early) cardiovascular diseases, specifically cardiomyopathy phenotypes, arrhythmias, and coronary artery disease, …

16 years of age All Phase N/A
B Brion Beerle, MD

The Alaska Oculocardiac Reflex Study

Observation study monitoring vital signs and anesthetic variables particularly heart rate during prospective, ocular manipulation and specifically uniform tension on extra ocular muscles during strabismus surgery. IRB approval from 1992 covered in letter from then IRB chair Dr. Judith Whitcomb, Anchorage, Alaska (letter 10/2020).

1 - 100 years of age All Phase N/A
C Carlo de Asmundis, MD, PhD

UZ Brussel HRMC Registry of Brugada Syndrome

The monocentric UZB registry for Brugada registry is intended to collect all data on patients affected by Brugada syndrome at UZ Brussel hospital (UZB).

18 - 100 years of age All Phase N/A
Y Yanxin Zhao

Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Multicenter, Observational Study (IAT-CLOSURE)

The main purpose of this study is to investigate the safety and outcomes of different treatment strategies, including best medical therapy (OAC [oral anticoagulation], antiplatelet [APT]) and left atrial appendage closure [LAAC] in acute ischemic stroke (AIS) patients with atrial fibrillation (AF) based on multimodal assessment from combined brain and …

18 years of age All Phase N/A
J Jan Niederdöckl, Dr.

Atrial Fibrillation at the Viennese University Emergency Department

The results of this study could imply that a atrial fibrillation registry, as a tool for structured diagnosis and therapy in patients with atrial fibrillation, may improve patient care for this rapidly growing population.

18 years of age All Phase N/A
V Vincent Probst, PUPH

Building of a Diagnostic/Prognostic Database for Human ERG Variant Effects

Cardiac channelopathies induce severe heart rhythm or conduction disorders. Mutations of the KCNH2 gene, that encodes the human (h) ERG channel, is responsible for 30-40% of all cases of long QT syndrome (inherited LQT2). Besides, hERG is frequently responsible for off-target effects of several pharmacological agents (acquired LQT2). With the …

years of age All Phase N/A

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