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arrhythmia Clinical Trials

A listing of arrhythmia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 572 clinical trials
B Bing Yang, MD

Effect of Prolonged Use of Dronedarone on Recurrence in Patients With Non-paroxysmal Atrial Fibrillation After Radiofrequency Ablation

Recurrence rate remains high after radiofrequency ablation in patients with non-paroxysmal atrial fibrillation(AF). Prolonged use of anti-arrhythmic drugs (AAD) beyond the post-ablation blanking has been adopted as a solution but without sufficient clinical evidence. Dronedarone is an AAD valid to maintain sinus rhythm and has fewer side effect than other …

18 - 80 years of age All Phase 4
G Gergana Lishkova, PhD, MD

From the Emergency Department Directly to Ablation of Atrial Fibrillation Study

The study is a prospective, two-arm, randomized, open-label, blinded endpoint, multi-center study to investigate the impact of first line ablation in patients presenting at the emergency room with recent-onset paroxysmal or persistent atrial fibrillation.

18 - 85 years of age All Phase N/A
D Dorthe Svenstrup, MD, Ph.D

Future Patient - Telerehabilitation of Patients With Atrial Fibrillation

This project has focus on patients with atrial fibrillation testing a telerehabilitation program for patients with atrial fibrillation.

18 years of age All Phase N/A
T Tamaz Shaburishvili, MD

Safety and Performance of ENDOMATIC SEPIOLA Left Atrial Appendage (LAA) Closure Device

The study is designed to evaluate the safety and performance of the ENDOMATIC SEPIOLA Left Atrial Appendage (LAA) Closure Device in Patients with non-valvular Atrial Fibrillation, who are at increased risk for stroke, and that cannot take, or have a reason to seek an alternative, to long-term anticoagulation therapy. Potential …

18 years of age All Phase N/A
P Pavel Osmancik, MD, PhD

Pulsed-field Ablation Vs. Sham Ablation to Treat AF

The study is planned as a single-blind, multicenter, prospective, randomized study. Sixty sbjects will be randomized 1:1 to either: (i) EP study + PFA, or (ii) EP study + Sham ablation control. After informed consent is obtained, an implantable loop recorder (ILR) will be implanted within seven days, and an …

18 years of age All Phase 3
S Stavros Stavrakis, MD, PhD

Synaptic Plasticity in the Epicardial Ganglionated Plexi

Atrial fibrillation (AF) is the most common arrhythmia and the prevalence increase with age. Autonomic nervous system play a critical role in the initiation and maintenance of AF. The intrinsic cardiac autonomic nervous system includes ganglionated plexus (GP) modulate the level of parasympathetic activity to the heart. Experimental and clinical …

21 - 90 years of age All Phase 1

Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation

The main purpose of this project is to evaluate the effects of high-intensity interval training (HIIT) compared to moderate-intensity continuous exercise training (MICE) and standard care on exercise capacity and quality of life in patients with persistent or permanent atrial fibrillation. Positive findings are vitally important for these patients, given …

40 years of age All Phase N/A
P Pavel Osmancik, MD, PhD

PRAGUE-25 Trial. Catheter Ablation vs. AADs and Risk Factor Modification.

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with a prevalence of 2% in general population. Incidence and prevalence of AF has been slightly increasing due to increasing age, improved ability to treat cardiac diseases, and higher incidence of obesity and other risk factors associated with AF. AF …

18 - 75 years of age All Phase 3
A Anne Rollin, MD

Hybrid Therapy and Heart Team for Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia with a prevalence ranging from 5% over 60 years old to 17% after 85 years old. Besides hemodynamical compromises and occurrence of heart failure, stroke remains the most feared complication related to AF with a risk increased by 5-fold. Catheter ablation …

18 years of age All Phase N/A
T Tammy Knight

QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)

Atrial fibrillation (AF) is a type of irregular heart rhythm due to electrical signal disturbances of the heart. It is a very common arrhythmia and the risk of developing AF increases with age and with other risk factors such as diabetes, high blood pressure, and underlying heart disease. The main …

18 years of age All Phase N/A

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