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blood-transfusions Clinical Trials

A listing of blood-transfusions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 91 clinical trials

Umbilical Cord Blood Transfusion in Consolidation Therapy of Elderly Patients With Acute Myeloid Leukemia

After complete remission, elderly AML patients cannot tolerate hematopoietic stem cell transplantation and standard-dose consolidation chemotherapy, and the 5-year survival rate is around 10%. Therefore, it is necessary to explore treatment strategy that can support chemotherapy or improve immunity. Umbilical cord blood is rich in hematopoietic stem cells and immune …

60 - 100 years of age Both Phase 1
J James Reynolds, PhD

S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion

The Purpose of the study is to test the hypothesis that administration of an S-nitrosylating (SNO) agent can improve tissue oxygenation during transfusion of packed red blood cells (RBCs).

18 - 35 years of age Both Phase 1
A Aimable Kanyamuhunga, MMed

Transfusion Camp for Medical Students in Rwanda

Transfusion medicine is closely linked with safe surgery. Transfusion Camp is a multidisciplinary educational project aimed at improving transfusion medicine knowledge in physicians. The course has been piloted in Rwanda, showing improvement in participant knowledge and confidence, resulting in its recommended implementation into the medical school curriculum. This project aims …

- 100 years of age Both Phase N/A
T Tingting Qi

Platelet Transfusion in Acute-on Chronic Liver Failure

Acute on-chronic liver failure (ACLF) is a severe liver disease with a 28-day mortality rate of up to 40%. When the patients get 3 or more organ failures, the 28-day mortality rate is up to 82.6%. Though the ACLF patients have high short-term mortality, and the only effective treatment method …

16 - 60 years of age Both Phase N/A
S Somaia Anwar, assistant lecture

Fresh Frozen Plasma Transfusion in Acute Organophosphate Poisoning

this study clinical trial to assess the role of fresh frozen plasma as a novel available and easy to be applied rather than conventional therapy on organophosphate poisoned patients and prediction of it is prognosis on selected patients and it is effect on outcome .

18 - 65 years of age Both Phase N/A
W Wu Fang, MD

Intravenous Immunoglobin Transfusion in Preterm Infants With Encephalopathy of Prematurity

Infection and inflammation is related to increased encephalopathy of prematurities.

- 6 years of age Both Phase N/A

A Trial Testing SP-420 in Subjects With Transfusion-dependent β-thalassemia

The goal of this clinical trial is to learn about SP-420 ability to remove iron from organs in subjects with transfusion-dependent β-thalassemia. The main questions it aims to answer are How efficient is SP-420 in cleaning iron from the liver? How is the safety and tolerability of ascending doses of …

18 - 100 years of age Both Phase 2
M Micah T Prochaska, MD, MSc

A Trial to Assess the Effect of Transfusion Strategies on Fatigability Levels After Hospital Discharge

This study is a randomized controlled trial in which hospitalized patients with anemia are randomized to receive transfusion at: a) Hb<9g/dL (liberal transfusion strategy), or b) Hb<7g/dL (restrictive transfusion strategy). We are measuring self-reported fatigability, fatigue, and activity levels at randomization and 7 days post hospital discharge in both trial …

18 - 100 years of age Both Phase N/A
R Ryan Metcalf, MD

Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence

Determine whether clinical decision support (best practice advisory) improves provider adherence to transfusion guidelines for all four major blood components (red blood cells, plasma, platelets, and cryoprecipitate) using a randomized study design to reduce risk of bias. Alerts will be visible to the experimental ordering provider group, while they will …

18 - 100 years of age Both Phase N/A
E Emily MacLeod

WithHolding Enteral Feeds Around Blood Transfusion (International)

The WHEAT International trial is a comparative effectiveness trial exploring whether withholding enteral feeds around the time of blood transfusion in very premature infants (<30 weeks) will reduce the occurrence of Necrotizing Enterocolitis (NEC). Currently both continued feeding and withholding feeding are approved care practices. The current study will randomize …

- 30 years of age Both Phase N/A

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