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kidney-failure Clinical Trials

A listing of kidney-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 634 clinical trials
M Maxime Taghavi, MD PhD

Arteriovenous Fistula Maturation in Hemodialysis Patients With or Without Positive Antiphospholipid Antibodies

Hemodialysis (HD) is one of the most often used modalities of blood epuration in ends-stage renal diseases (ESRD) and requires the creation of a patent vascular access such as an arteriovenous fistula (AVF). Native AVF is associated with lower morbidity and mortality compared to hemocatheters. AVF need a maturation process …

18 - 75 years of age All Phase N/A
M Maarten Taal

Application of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease

Research question: Can multiparametric renal Magnetic Resonance Imaging (MRI) provide structural and functional assessment of the kidneys to deliver prognostic information and guide treatment options in chronic kidney disease (CKD)? Aims and objectives: To establish a multiparametric renal MRI protocol in CKD cohorts. To use multiparametric MRI to characterise people …

18 - 75 years of age All Phase N/A
H Hendrik Bartolomaeus, MD

LONGitudinal Multi-omics Phenotyping of KIDney Function Alteration

This is a longitudinal observation of kidney function, immune system and gut microbiota before and 24 weeks after a live kidney transplantation conducted in donor and recipient pairs living in the same household. Outcome measures include kidney function, body composition, blood pressure, gut microbiome composition, metabolomics and immune cell states.

18 - 75 years of age All Phase N/A
L Laura Martinez, Dr.

Biomonitoring of Internal Exposure to MNPLs, and Its Effects, in Blood of Patients With Chronic Kidney Disease (CKD)

Micro and nanoplastics (MNPLs) effects on human heath is still preliminary. Chronic kidney disease (CKD) participants, specially does patients submitted to hemodialysis, are a population high exposed to plastics. The objective of our research is to be able to detect MNPLs on biological fluids of hemodialysis patients as well as …

18 - 85 years of age All Phase N/A
K Karine Chaussé

Transitioning to Home or In-center Dialysis

For people with advanced kidney disease, deciding which type of dialysis is best can be challenging. Studies have shown that quality of life is very important to patients. It is thought that the quality of life of people receiving their dialysis at home may be better than the one of …

18 years of age All Phase N/A
C Cédric Villain, MD, PhD

Geriatric Assessment for Older Kidney Transplantation Candidates

Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list. This study aims to evaluate the association between Geriatric assessment and inscription on kidney transplantation.

65 years of age All Phase N/A
D Ding Feng, PhD

Uremic Toxins and Outcomes in Chronic Kidney Disease

The aim of this cohort study is: To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic …

18 years of age All Phase N/A
X XINGZHI WANG, PHD.,MD

Effectiveness and Safety of Finerenone in Chinese CKD Patients Without Diabetes Mellitus

Background: This study aimed to evaluate the effectiveness and safety of Finerenone in patients with chronic kidney disease (CKD) without diabetes mellitus(DM), however, evidence based on both clinical trails and real-world data are limited. Methods Patients with CKD without DM were enrolled in this study from December 2022 to December …

20 - 75 years of age All Phase N/A
I Ignacio Manzur, MD

Early Detection of Chronic Kidney Disease

This retrospective observational study aims to assess the proportion of patients who were appropriately referred from primary care to the nephrology teleconsultation service. The appropriateness of the referral will be determined by the time elapsed between the referral criteria being met and the date of the teleconsultation, as well as …

18 years of age All Phase N/A
P Pearl Dulawan

DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve

This is a feasibility study to assess new, more practical ways of measuring renal reserve.

40 years of age All Phase N/A

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