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kidney-failure Clinical Trials

A listing of kidney-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 614 clinical trials
M Mohammed Kamran, PhD

EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality

Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the extent and basis of treatment failure in different patient populations. The vast majority of drug registration …

6 years of age All Phase N/A

Registry of Pre-mixed Solutions in Critically Ill Patients on the Continuous Renal Replacement Therapy

This is a multicenter, prospective, registry study. By collecting relevant demographic information and clinical data of patients receiving continuous renal replacement therapy (CRRT) with pre-mixed solutions, the clinical applicability of pre-mixed solutions will be evaluated in critically ill patients in real-world clinical settings. This study will be carried out in …

18 - 80 years of age All Phase N/A
S Sarah Yadavalli, Dr.

Amino Acid Loss During Continuous Renal Replacement Therapy

The goal of this observational study is to learn about amino acid loss during continuous renal replacement therapy and plasma amino acid levels in intensive care patients. The main questions it aims to answer are: What amount of amino acids is lost over the duration of continuous renal replacement therapy? …

18 years of age All Phase N/A
Y Yi Han, doctorate

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

To provide reference for clinical rational use of edoxaban; Optimize the individualized dosing regimen of edoxaban.

18 years of age All Phase N/A

Bowel Cleansing With Renal Impairment

Bowel preparation for colonoscopy requires the administration of large amounts of fluids that can cause fluid and electrolyte disturbances and volume overload, especially in patients with advanced renal failure. Polyethylene glycol-based regimens are considered safe, even in patients with advanced renal failure. However, the incidence of adverse effects (AEs) in …

18 - 80 years of age All Phase N/A
S Stavros Spiliopoulos, MD, PhD,

Ultra-low Dose Contrast for Endovascular Procedures

The purpose of this protocol is to study the safety and feasibility of using ultra-low dose iodinated contrast agent for infrainguinal endovascular revascularization procedures in patients with chronic limb-threatening lower limb ischemia (CLTI) and impaired renal function, in the new angiography suite of our department.

years of age All Phase N/A
K KATIE QURESHI

Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes

Patients living with diabetes mellitus have double the risk of kidney failure compared to patients without diabetes following use of dye in many x-rays and procedures to diagnose and treat narrowing of the arteries (blood vessels) in the heart that can lead to angina or a heart attack. Heart disease …

18 years of age All Phase N/A
V Valeska Bidault, MD

Study of the Quality of Life in School Aged-children With Posterior Urethral Valves

Posterior urethral valves (PUV) are the most common congenital obstructive lesion of the urethra, affecting from 1 per 3000 to 1 per 8000 live births. Valve ablation usually resolves the obstruction in PUV but patients still may suffer of deterioration in renal and urinary functions. Renal insufficiency is the most …

6 - 17 years of age Male Phase N/A

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. To address this …

21 - 80 years of age All Phase N/A
C Claire Rimes-Stigare, MD, PhD

Levosimendans Pharmacokinetics in Intensive Care Patients. An Observational Study.

Evaluation of the pharmacokinetics of levosimendan and its metabolites in intensive care patients with normal, reduced and dialysis supported renal function.

18 years of age All Phase N/A

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