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neoplasms Clinical Trials

A listing of neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,299 clinical trials
Q Quanda Liu Chief physician, MD

Clinical Efficacy of Transarterial Infusion Chemotherapy for Unresectable Colorectal Cancer

This is a prospective, multicenter, randomized, and open-label clinical trial. It is initiated to determine the efficacy of FOLFOX-based, transarterial infusion chemotherapy (TAIC) combined with either cetuximab or bevacizumab for patients with unresectable colorectal cancer (CRC).

18 years of age All Phase N/A
J Jennifer Ligibel, MD

Dance Study for Post-surgical Pain in Breast Cancer Survivors

The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, following mastectomy or lumpectomy.

18 years of age Female Phase N/A

ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

This study evaluates a fenretinide phospholipid suspension for the treatment of small cell lung cancer (SCLC).

18 years of age All Phase 1
Z Zhen Zhang, MD, PhD

Using ctDNA Methylation to Monitor Metastatic Colorectal Cancer Treatment (PROMET)

Multi-center observational clinical study to evaluate the application value of ctDNA methylation monitoring in efficacy assessment and relapse prediction in patients diagnosed with recurrence or metastatic colorectal cancer receiving radiotherapy plus SOC with or without PD-1.

18 - 75 years of age All Phase N/A
T Trial Manager

Safe De-escalation of Chemotherapy for Stage 1 Breast Cancer

The aim of this study is to assess the rates of circulating tumour DNA (ctDNA) in patients treated with surgery for stage 1 breast cancer that is HER2 positive or triple negative. The study will involve collecting blood samples from patients before and after surgery, if patients are enrolled after …

18 years of age All Phase N/A

Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer

This study is being done to determine if patients receiving personalized exercise therapy (versus those who do not receive personalized exercise therapy) have improved quality of life and physical functioning after completing their radiation therapy. Second, the study is being done to find if the quality of life changes during …

18 years of age Male Phase N/A
M Monique Steegers, Prof. dr.

Prevention of Opioid-induced Constipation in Patients With Advanced Cancer

More than 70% of patients with cancer in the palliative phase have pain that often requires treatment with opioids (morphine-like agents). Constipation occurs in 59% of patients treated with opioids. Opioid-induced constipation (OIC) has consequences that range from daily discomfort with social insecurity and disability to intestinal obstruction. It leads …

18 years of age All Phase 4
Y Ying Yang, MD

Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic Cancer

The purpose of this study is to evaluate the efficacy of thalidomide on improving the quality of life for metastatic pancreatic cancer patients receiving gemcitabine and nab-paclitaxel chemotherapy.

18 - 80 years of age All Phase 3
J Jiayuan Sun, MD, PhD

Transbronchial vs Transthoracic Ablation for Early-stage Peripheral Lung Cancer

The purpose of this study is to investigate the efficacy and safety of RFA through a transthoracic or transbronchial approach in the treatment of early-stage peripheral lung cancer.

18 years of age All Phase N/A
L Lauren Elliot

A Study of Alpelisib and Fulvestrant to Treat Endometrial Cancer

This is a 2 stage multi-center study designed to evaluate the efficacy of the combination of alpelisib and fulvestrant in patients with PIK3CA-mutated ER-positive endometrioid endometrial cancers by estimating the objective response rate (ORR). Treatment will continue until either unacceptable toxicity, progression of disease, or investigator/patient request for withdrawal.

18 years of age Female Phase 2

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