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neoplasms Clinical Trials

A listing of neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,196 clinical trials
N Nermeen S Habeeb, Doctor

B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers

Examine the role of B-catenin in differentiation of cutaneous squamous cell carcinoma from other lesions that may be similar to it

years of age All Phase N/A
X Xin Zhou, MD

Radiolabelled Nectin-4 Targeted LMW Probe PET/CT in Patients With Lung Lesions

To evaluate the ability of [68Ga]N188 to detect nectin-4 overexpression in patients with lung lesions.

18 - 75 years of age All Phase N/A
H Heather Etchevers, PhD

Understanding the Transition from Normal Melanocytes to Nevus to Melanoma

The primary objective of this study is to identify the molecular identity profiles of all cellular states that characterize the progression from benign nevi to malignant melanoma in CAYA patients with L/GCMN. The secondary objectives are: To longitudinally characterize the cell-free DNA (cfDNA) from CAYA patients. To improve the early …

years of age All Phase N/A
C Chiara Giorgini, MD

Usefulness of Post-Operative Radiotherapy in High-grade Cutaneous Squamous Cell Carcinoma: an Observational Study

Post-operative radiotherapy (PORT) is currently considered as the second most important therapy to treat high-grade cutaneous squamous cell carcinoma. Nonetheless, only few studies evaluate its impact on recurrence rate and the major part of those ones do not include a proper control group of patients. Most recent guide lines from …

18 years of age All Phase N/A
I Isabelle Ruchonnet-Métrailler, MD PhD

Congenital Lung Anomalies (CLA) Swiss Database

Congenital lung anomalies include different pathologies such as congenital cystic adenomatoid malformation, pulmonary sequestration, bronchial atresia, emphysema, bronchogenic cyst. They concern less than 1/10000 births and their physiopathological origin is still poorly understood. The main goal of this project is to pool the cases from different swiss centers on a …

- 16 years of age All Phase N/A
Y Yan Hu, M.D., Ph.D.

The Role of ctDNA Testing Plus AI-based Pathology in Resectable LSCC

The goal of this observational study is to explore whether ctDNA dynamic monitoring plus AI-based pathology can more effectively predict the therapeutic effect of neoadjuvant chemoimmunotherapy for resectable lung squamous cell carcinoma, so as to accurately guide clinical diagnosis and treatment.

18 - 75 years of age All Phase N/A
C Cheng Peng

Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy

The characteristics of the intestinal microbiota in high-risk colorectal polyp recurrence and their relationship with disease pathogenesis have not yet been fully elucidated. This study aims to analyze the microbial community characteristics in the intestinal mucosal tissue of patients after polypectomy with recurrence of colorectal polyps. Additionally, this research holds …

40 - 75 years of age All Phase N/A
C Chengzhi Zhou, Doctor

To Evaluate the Efficacy and Safety of Inhaled Corticosteroids Combined With Bronchodilators and Programmed Death-ligand 1 (PD-L1) Inhibitor Plus Platinum-based Chemotherapy in Patients With Advanced Lung Squamous Cell Carcinoma Complicated With Chronic Obstructive Pulmonary Disease (COPD)

To evaluate the efficacy and safety of inhaled corticosteroids combined with bronchodilators and programmed death-ligand 1 (PD-L1) inhibitor plus platinum-based chemotherapy in patients with advanced lung squamous cell carcinoma complicated with chronic obstructive pulmonary disease (COPD)

18 years of age All Phase N/A
A Anthony Kong, Dr

SOTO: Treatment Sensitivity of Organoids to Predict Treatment Outcome

In this study, we aim to assess whether Patient Derived Organoids can be used to predict treatment sensitivity in HNSCC patients.

18 years of age All Phase N/A
n nicolas feltes

Prostatic Size Reduction Following of Leuprorelin Acetate

To determine the possible reduction in prostate size following the administration of Leuprelin prior to the application of radiotherapy.

18 - 95 years of age Male Phase N/A

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