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neoplasms Clinical Trials

A listing of neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,180 clinical trials
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Identification of Pathways to Mitigate Immune-Related Adverse Events With Cancer Immunotherapy

This protocol is a prospective, observational study of participants receiving immunotherapy (checkpoint inhibitors, CPI) for cancer therapy, testing the hypothesis that patients with immune related cutaneous adverse events (ircAEs) have unique immunologic endotypes associated with polarized immune responses.

18 years of age All Phase N/A
C Colin E Champ, MD, CSCS

EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.

20 - 89 years of age All Phase N/A
V Vanessa Stadlbauer, MD

Role of the Gut Microbiome in Anti-tumor Therapy Induced Diarrhea

The role of the gut microbiome in the development of side effects of anti cancer treatment will be assessed in this longitudinal cohort study.

18 years of age All Phase N/A
B Ben O'Leary

ORganoid GeneratioN Study for Cancer

ORIGINS - a multi-site sample collection study to establish patient-derived pre-clinical models for cancers

18 years of age All Phase N/A
L Lu Wenchao, Master

Discovery of Biomarkers Related to the Efficacy and Adverse Reactions of Immune Checkpoint Inhibitors Based on Metabolism-genomics

Immune checkpoint inhibitors (ICIs) are an important breakthrough in cancer therapy and have been increasingly used.However, ICIs can cause a unique spectrum of side effects termed immune-related adverse events (irAEs),which can affect any organ systems and in some cases are fulminant or even fatal.In clinical practice, irAEs and clinical efficacy …

18 - 80 years of age All Phase N/A
M Michael Milosevic, MD

Magnetic Resonance-Guided Adaptive Radiotherapy (MRgART) Using an Integrated Magnetic Resonance Linear Accelerator (MRL)

This study is being done to help further understand how MR-guided adaptive RT in conjunction with the Integrated Magnetic Resonance Linear Accelerator (MRL) can improve patient outcomes. This study will include participants who will be receiving radiotherapy using the MRL machine to target their cancer more precisely. Participants will be …

18 years of age All Phase N/A
C Clinical Trial Referral Office

Patient Derived Preclinical Models

Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models. This study is being done to …

18 years of age All Phase N/A
C Catherine Trigwell

Investigating the Tumour Immune Response of Radiotherapy

This study aims to investigate immune changes which occur before and following standard radiotherapy in a range of tumour types. We will collect tissue and blood samples before and after radiation treatment from participants across six cancer types: cervical, rectal, Head and Neck cancer, nodal non-Hodgkin lymphoma, cutaneous lymphoma and …

18 years of age All Phase N/A
L Lukas Kessler, MD

FAPI-PET for Tumor Detection

This is a prospective observational trial investigating correlation with histopathology, positive predictive value, detection rate, reproducibility and impact on clinical management of 68-Ga-FAPI PET/CT or PET/MRI in patients receiving this imaging modality for tumor staging or restaging as part of clinical care.

18 years of age All Phase N/A
M Manali I Patel, MD MPH MS

Impact of the Coronavirus (COVID-19) on Patients With Cancer

The purpose of this study is to understand the impact of COVID-19 on patients with cancer through a survey.

18 - 99 years of age All Phase N/A

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