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Atrial Fibrillation Clinical Trials

A listing of Atrial Fibrillation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 473 clinical trials
P Pavel Osmancik, MD, PhD

PRAGUE-25 Trial. Catheter Ablation vs. AADs and Risk Factor Modification.

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with a prevalence of 2% in general population. Incidence and prevalence of AF has been slightly increasing due to increasing age, improved ability to treat cardiac diseases, and higher incidence of obesity and other risk factors associated with AF. AF …

18 - 75 years of age All Phase 3
T Tammy Knight

QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)

Atrial fibrillation (AF) is a type of irregular heart rhythm due to electrical signal disturbances of the heart. It is a very common arrhythmia and the risk of developing AF increases with age and with other risk factors such as diabetes, high blood pressure, and underlying heart disease. The main …

18 years of age All Phase N/A
M Mary Li

Evaluation of MRI-conditional 12-lead ECG

With MRI's increasing role in detecting central nervous system and orthopedic diseases, patients with ischemic history are increasingly referred for MRI exams. Currently, 3-lead ECG gating systems are utilized during cardiac MRI scanning as standard of care. However, this monitoring system is often insufficient to evaluate for the development of …

18 - 90 years of age All Phase N/A
J Jonathan Steinberg

Renal Denervation + PVI vs PVI Alone for Persistent AF

Pulmonary vein isolation (PVI) is the cornerstone of ablation for atrial fibrillation (AF). Increased cardiac sympathetic stimulation can facilitate AF and reduction can be accomplished by renal artery denervation (RDN). The recently completed randomized trial, ERADICATE-AF, convincingly demonstrated that RDN plus PVI resulted in a reduction in recurrent incident AF …

18 years of age All Phase N/A
M Marcin Demkow, MD PhD

Optimal Antiplatelet Therapy Following Left Atrial Appendage Closure

SAFE-LAAC Trial has been designed to gather data on the most optimal strategy of antiplatelet therapy after transcatheter left atrial appendage occlusion with Amplatzer or WATCHMAN device

18 years of age All Phase 4
S Shady Nahkla, MD

Intracardiac Echocardiography Guided Watchman Device Implant

This study is to look at the success of Intracardiac Echocardiography (ICE) in the Watchman procedure. Currently the process is to use a Transesophageal Echocardiography (TEE) to place the Watchman in patients. This study is aiming to show how the ICE is just as effective in placing the device correctly …

18 years of age All Phase N/A
P Patrick Swojanowsky, MD

Vagal Nerve Stimulation for the Treatment of Persistent AF

The goal of this clinical trial is to answer the question whether a transcutaneous stimulation of a certain nerve (Nervus vagus) with a dedicated device reduces the recurrence of the heart rhythm disorder atrial fibrillation. Participants will receive a dedicated nerval stimulation device and will treat themselves on a daily …

18 years of age All Phase N/A
M Mary Jane Strickland

CardioFocus HeartLight Post-Approval Study

This is a post-approval study to evaluate the clinical outcomes in a cohort of participants treated during commercial use of the HeartLight System to confirm results of the previously conducted pivotal clinical study.

18 years of age All Phase N/A
Y Yan Wang, PhD

Three Dimensional Navigation IntraCardiac Guidance Kit for Atrial Septal Puncture

This study aims to evaluate the safety and efficacy of a three-dimensional navigation intracardiac guidance kit to perform atrial septal puncture in patients requiring catheter ablation, which will be compared with procedures using traditional kit for atrial septal puncture.

18 - 75 years of age All Phase N/A
A Anita Zadori, MD, PhD

The Role of Multimodality Imaging in Left Atrial Appendage Closure

The aim of the present prospective, randomized single-centre study is to examine the success rate, safety, overall preoperative and operative burden and long-time outcome of percutaneous left atrial appendage closure procedures after unimodal and multimodal preprocedural imaging. According to the investigators' primary hypothesis, simple, unimodal preprocedural imaging does not increase …

18 years of age All Phase N/A

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