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autonomic-nervous-system Clinical Trials

A listing of autonomic-nervous-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 105 clinical trials
H Helen Yoo, Ph.D.

Vagus Nerve Stimulator for Autism and Other Developmental Disorders

The goal of this flexible single-subject design vagus nerve stimulation (VNS) study is to examine the behavioral, cognitive, and biorhythmic effects of VNS in children and adults with autism and developmental disabilities. The main aims are: Pilot the creation of a profile for those who will respond to VNS with …

12 - 40 years of age All Phase N/A
J Jill Wecht, EdD

Autonomic Effects of Stimulation in SCI

This study aims to determine the effects of transcutaneous spinal cord stimulation to increase blood pressure and use that device to increase exercise endurance time and heart rate recovery during arm cycle ergometry. In addition, the investigators will see if the stimulation helps regulate body temperature when in a cool …

35 - 50 years of age All Phase N/A
R Roberto Tarud

Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy

This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical …

18 years of age All Phase 4
F Fady Girgis, MD

Occipital Nerve Stimulation in Trigeminal Autonomic Cephalgias

The objective of this study is to determine the efficacy of occipital nerve stimulation (ONS) in the treatment of chronic trigeminal autonomic cephalalgias (TACs).

18 - 100 years of age All Phase N/A
A Adrien Waeber

Obstructive Sleep Apnea - Autonomic and Vascular Exploration

The goal of this clinical trial is to assess the effect of CPAP withdrawal on vascular and autonomic function in patients with obstructive sleep apnea. The main question it aims to answer is: • Is the pulse wave amplitude index able to predict the impact of sleep apnea treatment withdrawal …

18 years of age All Phase N/A
K Kris Gray

Autonomic Control of the Circulation and VDR

The study objective of this project is to examine the mechanisms of the venous distension reflex (VDR) in humans. We hypothesize that COX blockade with ketorolac tromethamine, an intravenous NSAID, will attenuate the muscle sympathetic nerve activity (MSNA) response to limb venous distension. To gain further insight into whether the …

21 - 35 years of age All Phase N/A
C Camillo Marra, MD

Autonomic Involvement in Patient With Cognitive Decline

Prospective interventional study with a device for comparing autonomic parameters among patients with different forms of cognitive decline

50 - 85 years of age All Phase N/A
Z Zachary Pohlkamp

Deciphering Preserved Autonomic Function After Multiple Sclerosis

This study looks to characterize gradients of dysfunction in the autonomic nervous system in patients with clinically diagnosed multiple sclerosis. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with multiple sclerosis typically suffer. Focusing on blood …

18 - 50 years of age All Phase N/A
R Ryan Solinsky, MD

Deciphering Preserved Autonomic Function After Spinal Cord Injury

This study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically suffer. Focusing on blood pressure regulation, …

18 - 50 years of age All Phase N/A

Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation

Prospective cohort study evaluating the electrophysiologic and biochemical effects of stellate ganglion block in patients with ventricular tachycardia.

18 years of age All Phase N/A

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