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cardiac-surgery Clinical Trials

A listing of cardiac-surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 266 clinical trials

Endothelial Dysfunction and Non-cardiac Surgery

Endothelial dysfunction is a cardiovascular disease hallmark. After non-cardiac surgery, cardiovascular events correlate with surgical outcomes. Understanding the role of endothelial function in these events is crucial. This research aims to study endothelial function and its association with cardiovascular events.

45 years of age All Phase N/A
T Thepakorn Sathitkarnmanee, MD

Postoperative Atrial Fibrillation in Cardiac Surgery

This multicenter observational study aims to investigate the incidence and identify risk factors associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery at three medical centers in Thailand. The study will examine patient characteristics, surgical factors, and anesthetic management practices that may contribute to the development of this …

18 years of age All Phase N/A

Platelet and Autotransfusion Device in Cardiac Surgery

Cardiac surgery is a bleeding-risk surgery and frequently requires blood transfusion. Intraoperative autotransfusion devices are used to aspirate, process and retransfuse patients' blood. These devices are effective in recovering red blood cells and limiting the need for transfusion of packed red blood cells. Some devices, such as I-SEP's SAME®, can …

18 years of age All Phase N/A
S Sophie Robichaud, RRT

Right Ventricular Pressure Waveform Monitoring in Cardiac Surgery

RV dysfunction has been associated with increased mortality in the ICU and cardiac surgical patients. Thus, early identification of RV dysfunction at less severe stages will allow for earlier intervention and potentially better patient outcomes. However, so far, no studies have reported prospectively the prevalence of abnormal RV pressure waveform …

18 years of age All Phase N/A
L Lytfi Krasniqi, MD

Inflammation and Postoperative Atrial Fibrillation in Cardiac Surgery

Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, marked by an irregular and rapid heart rate, and associated with increased morbidity, longer hospital stays, and higher costs. Its complex pathophysiology involves atrial remodeling, inflammation, and autonomic dysregulation. Surgical trauma and cardiopulmonary bypass trigger an inflammatory response, releasing …

18 - 99 years of age All Phase N/A
K K van Loon, MD, PhD

Cerebral Blood Flow in Neonates During Major Cardiac Surgery.

Rationale: During cardiac surgery, neonates are at high risk of cerebral damage: 36-78% will have new cerebral lesions after surgery. Adequate cerebral perfusion (CBF) is mandatory to prevent postoperative brain damage and neurobehavioral outcomes. For CBF, the systemic blood pressure should be managed above the brain's critical closing pressure (CrCP), …

- 6 years of age All Phase N/A

Patient Blood Management in Patients Scheduled for Cardiac Surgery

The ICARUS 2 study has the general objective of collecting data in patients undergoing cardiac surgery; in our centre, in order to optimize and improve hemoglobin values, a team of haematologists, assisted by cardio anesthetists and cardiac surgeons, will evaluate the blood tests of patients scheduled for elective cardiac surgery …

18 years of age All Phase N/A
H Huanlei Huang Phd

Surgical Treatments of Tricuspid Valve Regurgitation After Cardiac Surgery

This study aims to present our center's experience in managing postoperative tricuspid valve regurgitation over the past 25years and to analyze the outcomes of these surgical treatments.

16 years of age All Phase N/A

Differential Regulation of RAAS-axis in Patients Undergoing Cardiac Surgery

This study investigates the question of whether there are differences in the plasma concentration of hormones of the RAAS-axis between patients undergoing on-pump cardiac surgery and those receiving off-pump surgery

18 years of age All Phase N/A
M Mickael VOURC'H, MD

Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic

This study will describe the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will focus on hemodynamic failure and organ dysfunction after surgery. Capturing real-world data and sharing international experience will inform the management of this complex group of patients who undergo surgery throughout the COVID-19 …

18 years of age All Phase N/A

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