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cardiac-surgery Clinical Trials

A listing of cardiac-surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 266 clinical trials
S Salah Eldin Ahmed Abdeluaziz, master

The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery

To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery

years of age All Phase N/A

Effect of Stress Ball During Chest Tube Removal After Open Heart Surgery

15 minutes before the procedure, nurses (FEÖ and NT) will explain and demonstrate how to use the stress ball. The stress ball will be applied for approximately five minutes, including the chest tube removal procedure. A round, medium-hard, high-quality silicone ball, approximately 6 cm in diameter, will be used. Patients …

18 years of age All Phase N/A
H Hugo Tremblay, Bachelor

Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery

Standard Heparin management, based on total body weight, is not well established for obese patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The purpose of this study is to assess the safety and efficacy of using lean body mass (LBM) to determine pump flow rate and/or Heparin dosage in obese …

18 years of age All Phase N/A
Y Yuri Y Vechersky, PhD

The Effect of Colchicine on the Occurrence of Atrial Fibrillation After Cardiac Surgery

Development of a new comprehensive method for perioperative prevention of atrial fibrillation paroxysms in cardiac surgery patients at the hospital stage. It is planned to recruit 70 patients who will undergo pericardial fenestration during the operation using the original technique during coronary artery bypass grafting (Patent No. 2647626 C1 Russian …

18 years of age All Phase 4
S Sam Rudow

ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)

The purpose of this research is to evaluate the use of Angiotensin II in patients with low blood pressure post-surgery. Your information will be collected for 28 days post the procedure and initiation of the study drug to assess for safety events and complications.

18 years of age All Phase 4
Y Yi-Ting Chang, MD

ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial

This clinical trial compares analgesia efficiency and recovery outcomes between two different fascial plane block techniques (ESPB vs.PIFB) in cardiac surgery patients participant population/health conditions]. The main questions it aims to answer are: Does ESPB provide superior analgesia than PIFB Do patients who receive ESPB have better recovery outcomes

18 years of age All Phase N/A
M Muhammad Saad Yousuf, MBBS, FCPS

Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery

The goal of this study is to evaluate the effects of steroids on the early postoperative inflammatory response in patients undergoing elective pediatric congenital cardiac surgery, requiring cardiopulmonary bypass (CPB).

1 - 18 years of age All Phase 4
H Head of Pediatric Emergency and Intensive Care Division

High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery

High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery

- 18 years of age All Phase N/A
A Annegret Kauert-Willms, MD

Point-of-care Measurement of the Antifibrinolytic Activity of Tranexamic Acid in Cardiac Surgery

Tranexamic acid (TXA) is a widely used antifibrinolytic agent that can reduce postoperative blood loss and packed red blood cell transfusions during cardiac surgery. Previous (in-vivo) studies have measured TXA plasma concentration and associated clinical effect (e.g. blood loss). Patient blood management guidelines recommend the routine use of TXA in …

18 - 90 years of age All Phase 4
C Christophe Beyls, MD

Norepinephrine Weaning Guided by the Hypotension Prediction Index in Vasoplegic Shock After Cardiac Surgery

In postoperative cardiac surgery under extracorporeal circulation, the patient may develop a vasoplegic syndrome, characterized by arterial hypotension (mean arterial pressure (MAP) < 65 mmHg); a decrease in vascular resistance and a cardiac output that may be normal or increased, and increased postoperative mortality/ International recommendations recommend the prescription of …

18 years of age All Phase N/A

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