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Kidney Disease Clinical Trials

A listing of Kidney Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 867 clinical trials
K Karly Gunson, HBA, BHSc

ODYSSEE Kidney Health Trial

INTRODUCTION Severe CKD is defined as a risk of greater than 10% for progressing to RRT [home hemodialysis (HHD), home peritoneal dialysis (HPD), and transplantation] within 2 years. There is a need to improve access to CKD self-care counselling and RRT education for patients with severe CKD. Trials of CKD …

18 years of age All Phase N/A
W Wei Zhen Hong

Nurse-led Physician-supported Care for Patients With Chronic Kidney Disease and Multimorbidity

Chronic kidney disease (CKD) is a prevalent chronic disease and is often intertwined with the management of cardiovascular disease and the optimization of metabolic risk factors. In light of steeply rising rates of end-stage kidney disease (ESKD) and increased healthcare resource utilization by CKD patients, the investigators propose that the …

21 years of age All Phase N/A
M Mohamed A Mohamed, MSc

Renoprotective Effects of Dapagliflozin Versus Pentoxiphylline in Chronic Kidney Disease Patients

Kidneys have a vital role in glucose homeostasis by various mechanisms, one of the major mechanisms is through SGLT2. This role was commonly overlooked till development of the new SGLT2 inhibitors. (Ni, L., et al 2020) The SGLT2 inhibitor class of glucose-lowering agents has recently shown beneficial effects to reduce …

18 - 60 years of age All Phase 3
R Rik Olde Engberink, MD PhD

The Role of Skin Sodium Accumulation in Chronic Kidney Disease

This project consists of four substudies: a cohort study (A) and a sodium intake intervention (B) and a sodium excretion intervention (C) and a water intervention study (D). The main objective of the cohort study (A) is to investigate the prognostic implications of tissue sodium accumulation in CKD patients. The …

18 years of age All Phase N/A
D Dennis Kannenkeril, MD

Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney Transplantation

The aim of this study is to observe the mechanisms of dapagliflozin on the renal interstitial tissue and renal perfusion. For this purpose, renal transplanted patients as an excellent model of CKD and high cardiovascular risk (similar to patients in DAPA-CKD study) are included in this study. The objectives of …

18 - 75 years of age All Phase 4
J Jeanie Park, MD

Handgrip Exercise Training and CKD

The purpose of this study is to find out if regular handgrip exercise performed at home can improve blood pressure at rest and during exercise in patients with chronic kidney disease (CKD). This study is also intended to understand what causes an increase in blood pressure at rest and during …

45 - 85 years of age All Phase N/A
J Jill LoGuidice

Physical Activity in CKD

The goal of this is to test the efficacy of a 12-week physical activity intervention in 64 adolescents with CKD.

13 - 18 years of age All Phase N/A

Kidney Health: Eat Well, Live Well

This two-arm, parallel randomized trial study will assess the efficacy of a 6-month (26 weeks) community-based program in reducing kidney injury (as Urine Albumin to Creatinine ratio, uACR), cardiovascular risk (as Hemoglobin A1C and blood pressure), mental health (as PHQ-8) and diet quality (as fruits and vegetables intake and Healthy …

18 years of age All Phase N/A
D Denise Mafra, phd

Beetroot Extract Supplementation Associated With an Exercise Protocol for Chronic Kidney Disease Patients

Chronic kidney disease (CKD) patients often present systemic inflammation and oxidative stress, resulting in metabolic disorders and high rates of disease-associated cardiovascular death. The literature has indicated that dietary control, the use of bioactive compounds, and the practice of regular physical exercise are essential for the prevention and management of …

18 - 65 years of age All Phase N/A
H Hongxia Shen, Phd

EHealth Based Self-management Intervention for Chronic Kidney Disease Care in China

The purpose of this study is to develop an evidence-based tailored eHealth self-management intervention for patients with chronic kidney disease in China, and test the impact on implementation and effectiveness of interventions.

18 years of age All Phase N/A

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