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uterine-fibroids Clinical Trials

A listing of uterine-fibroids medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 46 clinical trials
W Wouter Froyman, MD, PhD

Temporary Artery Clipping for Robotically-assisted Myomectomy, a Multicentric Randomized Controlled Trial

This study aims to investigate the efficacy of temporary clipping of the uterine artery and utero-ovarian ligament during robotically assisted myomectomy (RAM) for uterine fibroids. While RAM is increasingly used for myomectomy, bleeding control remains challenging. Temporary clipping of arteries has shown promise in conventional laparoscopy but has not been …

18 years of age Female Phase N/A
P Priscilla Machado

Evaluation of Uterine Fibroids by CEUS and SHAPE Pre and Post UAE

This study goals are to determine the patterns of uterine fibroid vascularity pre and post UAE using CEUS resulting in an alternative to gadolinium-enhanced MRI that is less expensive, has less contra-indications and side effects, is real time, and noninvasive helping physicians to evaluate the result of UAE procedures. Also, …

18 years of age Female Phase 2
V Véronique Othenin-Girard

The Impact of a Novel GnRH Antagonist With Add-back Therapy for Treatment of Uterine Fibroids and Endometriosis on Hemostasis Parameters

Uterine fibroids and endometriosis are two frequent diseases among women of reproductive age. They can be responsible for chronic and/or menstrual pelvic pain and abnormal uterine bleeding. The first-line management of these conditions relies on medical treatment. Hormonal treatment with contraceptive pill can be effective, although up to 30% of …

18 years of age Female Phase N/A
S Shing Chee Symphorosa CHAN

HIFU Versus Myomectomy for the Treatment of Symptomatic Uterine Fibroids

The goal of this clinical trial is to learn if High-Intensity Focused Ultrasound (HIFU) is as effective as myomectomy for treating symptomatic uterine fibroids in women aged 18 to 50. The main questions it aims to answer are: Is HIFU as effective as myomectomy in improving quality of life for …

18 - 50 years of age Female Phase N/A

Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

The goal of this clinical trial is to determine the benefit of relugolix 40 milligrams (mg) once a day compared with placebo in heavy menstrual bleeding associated with uterine fibroids. The main question[s] it aims to answer are: the benefit of relugolix 40 mg once daily in women with heavy …

18 - 50 years of age Female Phase 3
F Fang Zhao, MD

Safety and Efficacy of Using a Novel Full Visual Access Platform System in Transvaginal Hysterectomy

The modified vNOTES hysterectomy was accomplished and validated for efficacy and safety using a multi-access vaginal confinement instrument with a fully visualised vaginal access platform.

- 60 years of age Female Phase N/A
M Massimo Stomati, Ph.D

Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid

The study will evaluate the impact on uterine fibroids' volume of a combination of natural molecules including Epigallocatechin gallate, Vitamin D, D-chiro-inositol and Vitamin B6. The patients will be evaluated at baseline and after three months of treatment with placebo or product.

30 - 40 years of age Female Phase 3
K Kirsi M Joronen, MD PhD

Treatment of Benign Uterine Disorders Using High Intensity Focused Ultrasound (MR-HIFU)

MRI-guided high intensity focused ultrasound (MRI-HIFU) has been proven to be a safe and effective method in treating uterine fibroids and also adenomyosis. However, systematic studies on the effect of this treatment on factors affecting fertility are still lacking. Also quite little is known about body's systemic response to MRI-HIFU. …

18 - 50 years of age Female Phase N/A

Effect of Vitamin D3 Supplementation on Symptomatic Uterine Fibroid in Women With Vitamin D Deficiency

39 women with symptomatic uterine fibroid with serum vitamin D deficiency will receive vitamin D3 supplementation for 6 month.then symptoms and size of fibroid will be re evaluated..

18 - 50 years of age Female Phase N/A
C Catherine P Haering, BA

QL Block in Laparoscopic Myomectomy

This study aims to determine the efficacy of a quadratus lumborum (QL) block in decreasing postoperative pain in patients undergoing myomectomy for uterine fibroids. A QL block is a temporary anesthetic injection in the quadratus lumborum muscle, a muscle in the lower back, that has been previously shown to significantly …

18 - 45 years of age Female Phase 4

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