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sarcoidosis Clinical Trials

A listing of sarcoidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 49 clinical trials
V Virginia Mihalick, MS

Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis

Sarcoidosis is a heterogeneous disorder of unknown etiology whose signature lesions are granulomatous inflammatory infiltrates in involved tissues. Tissue commonly affected are lungs, skin, eyes, lymph nodes and the heart. In this latter case, cardiac sarcoidosis (CS) can lead to atrioventricular (AV) blocks, ventricular arrhythmias, heart failure (HF) and sudden …

21 - 100 years of age Both Phase 2
C Christian L Polte, MD, PhD, MSc

Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis

This prospective imaging study investigates the diagnostic ability of Gallium-68 DOTA-TOC (68Ga-DOTA-TOC) positron emission tomography/computed tomography (PET/CT) in the clinical work-up of patients with 1) clinically suspected acute myocarditis (n=30-40) and 2) clinically suspected cardiac sarcoidosis (n=30-40) using clinical diagnostic criteria as well as endomyocardial biopsy as reference. Furthermore, 68Ga-DOTA-TOC …

18 - 85 years of age Both Phase N/A
J Judy McConnell

Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis

This randomized pilot clinical trial aims to examine whether sample collection with Franseen-type needles are effective for the diagnosis of sarcoidosis, as defined by improved sample quality for pathological diagnosis compared to the conventional Menghini-type needle.

18 - 100 years of age Both Phase N/A
J John O. Prior, MD, PhD

[68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation

Acute myocardial inflammation is an heterogenic syndrome involving different clinical pathologies with different outcome. For the purpose of this study protocol, we focuse on three entities of this syndrome, namely the acute cellular cardiac allograft rejection (ACR), cardiac sarcoidosis (CS) and the immune checkpoint inhibitor induced myocarditis (ICIM), for which …

18 - 100 years of age Both Phase 2
H Han W Kim, MD

Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis

The primary objective of this study was to determine the ability of cardiac magnetic resonance (CMR) to identify cardiac involvement in patients with sarcoidosis. Patients were to undergo CMR in addition to routine clinical evaluation.

18 - 100 years of age Both Phase N/A
A Alicia K Gerke, MD

Worldwide Sarcoidosis Research Study

The aim of this study is to collect information about the clinical course and characteristics of sarcoidosis patients around the world through web-based surveys. Recruitment is directed at and driven by patients in the sarcoidosis community. This will allow the the investigators to study sarcoidosis patients across all demographic, geographic, …

18 - 100 years of age Both Phase N/A
R Rebecca A Epstein, MPH

Foundation for Sarcoidosis Research Advanced Cures Registry (FSR-SARC Registry)

The goal of the study is to create a longitudinal study of patient reported outcomes for people living with sarcoidosis that maintains privacy. Patients report on the following: demographics, disease symptoms, diagnostic journey, provider experience, disease treatment, and burden of disease. The goal is to create a natural history of …

7 - 100 years of age Both Phase N/A
F Fausto Leoncini, MD

Endobronchial Ultrasound Strain Elastography in Sarcoidosis

Strain elastography (SE) is an imaging method used for the measurement of relative tissue elasticity through qualitative (color pattern) or semi-quantitative methods (strain ratio or strain histogram). Very recently, the first pilot study has provided preliminary evidence that EBUS-SE elastography may help identify fibrotic lymph nodes in sarcoidosis and that …

18 - 100 years of age Both Phase N/A
N Nicholas Wozniak

Mayo AVC Registry and Biobank

Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous. Diagnosis and screening of blood-relatives is very difficult as the disease process can be subtle, but …

- 100 years of age Both Phase N/A
K Kimberly Donnelly, Ph.D.

Interstitial Lung Disease Research Unit Biobank

Establish a interstitial lung disease (ILD) registry and biorepository to lead towards a further understanding of the disease.

18 - 100 years of age Both Phase N/A

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