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Peripheral Vascular Disease Clinical Trials

A listing of Peripheral Vascular Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 153 clinical trials
R Ryan Mays, PhD, MPH, MS

Community-based Exercise Following Revascularization for PAD

The primary goal of this clinical trial is to evaluate whether a community-based structured exercise therapy (CB-SET) intervention, which could be accessible and easily disseminated, adds benefit to peripheral artery disease (PAD) patients undergoing revascularization (REVASC) to improve their function and cardiovascular health.

40 - 90 years of age All Phase N/A
Y Yang Yongjiu

ACOART BTK RENEW:A Post Market Clinical Study

The objective of this prospective, multi-center, single arm study is to obtain further data on the safety and performance of the Acotec Litos&Tulip Drug-coated Balloon catheters in the treatment of lesions in below-the-knee artery.

18 - 75 years of age All Phase N/A
D Diane Treat-Jacobson, PhD

Intermittent Pneumatic Compression With and Without Exercise to Improve Functioning in Peripheral Artery Disease

The INTERCEDE randomized trial will establish whether six-months of intermittent pneumatic compression combined with walking exercise improves walking endurance at six-month follow-up, compared to walking exercise + sham compression therapy, in people with lower extremity peripheral artery disease (PAD). The INTERCEDE trial will also determine whether intermittent pneumatic compression therapy …

55 years of age All Phase N/A
A Arash Harzand, MD

Exercise Therapy for PAD Using Mobile Health

Peripheral artery disease (PAD) is a highly prevalent condition affecting up to 10% of Veterans that leads to loss of walking ability and increased risk of amputation. Veterans have limited access to supervised exercise therapy, a facility-based program proven to improve walking ability in PAD, which is poorly attended due …

40 years of age All Phase N/A
D Diane Treat-Jacobson, PhD

The COCOA-PAD II Trial

Among people with peripheral artery disease (PAD) age 55 and older, the investigators will test the hypothesis that PAD participants randomized to cocoa flavanols will have greater improvement or less decline in six-minute walk distance at six-month follow-up, compared to those randomized to placebo. The study will randomize 190 participants …

55 years of age All Phase 3
K Kaichuang Ye, MD, PhD

Stents Post-dilation With DCB or POBA in Femoropopliteal Arteries

To compare the efficacy and safety of stent angioplasty with Orchid 035 Drug Coated Dilatation (DCB) and Plain Old Balloon Angioplasty (POBA) for post-dilatation for long (>10cm) femoropopliteal chronic total occlusion.

18 - 80 years of age All Phase N/A
J Janet Klein, RN

Leg Heat Therapy in Peripheral Artery Disease

The goal of this randomized, double-blind, sham-controlled clinical trial is to evaluate the benefits of home-based, leg heat therapy (HT) on lower-extremity functioning and quality of life in patients who suffer from lower-extremity peripheral artery disease (PAD). We will randomize 106 patients to one of two groups that either receive …

60 years of age All Phase N/A
W Wei Guo

Safety and Effectiveness of the Peripheral Balloon-Expandable Covered Stent System for Iliac Artery Stenosis/Occlusion. (SELECT)

This is a prospective, multi-center, single-arm clinical trial to evaluate the Peripheral Balloon-Expandable Covered Stent System for treating stenosis and/or occlusion in the common and external iliac arteries. The safety and effectiveness of the stent system will be compared to pre-set performance goals. All treated subjects will have follow-up visits …

18 - 80 years of age All Phase N/A
D Daniel Xu

Improving Walking Performance in Patients With Peripheral Artery Disease Through Wearable Activity Trackers

Peripheral Arterial Disease (PAD) of the lower extremities is common and prevalence of PAD is increasing in our aging population. The presence of PAD is associated with increased cardiovascular morbidity and mortality, reduced physical function and quality of life. Intermittent claudication is the most common symptom of PAD affecting about …

years of age All Phase N/A

Using Near-Infrared Light to Better Understand Peripheral Artery Disease

The goal of this study is to better understand how blood flows and how oxygen is utilized in the lower limbs of people who suffer from peripheral artery disease. This study will also assess how these factors affect treatment outcomes. Specific aims include: Aim 1: Utilize BB-NIR-DCS to differentiate PAD …

18 years of age All Phase N/A

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