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dementia Clinical Trials

A listing of dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 793 clinical trials
S Sazzadul Islam, M.Sc.

Cognitive Health Awareness Program in Surgical Patients

Addressing brain health and cognitive impairment (CI) in the aging population is important, especially in those undergoing surgery. While certain adverse outcomes are beyond control due to various factors, some may be preventable, such as delirium. It is crucial for patients and their families to be fully aware of the …

60 years of age All Phase N/A
F Francesca Farina, PhD

Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk

By age 45, women's lifetime risk of dementia is estimated to be 1 in 5. Two-thirds of people currently living with a dementia diagnosis are women, and-women make up the majority of carers for people with dementia. Because women bear a larger burden of the dementia epidemic, they tend to …

40 - 58 years of age Female Phase N/A
B Barry Greenberg, PhD

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

To investigate the effect of trazodone on sleep, hippocampal-dependent memory and hippocampal excitability. The investigators hypothesize that trazodone will improve total sleep time and proportion of time in Slow Wave Sleep (SWS).

55 years of age All Phase 2
X Xingqi Wu, M.D.

Effect of Transcranial Alternating Current Stimulation(tACS) for Early Alzheimer's Disease

To investigate the clinical effect neural mechanism of transcranial alternating current stimulation in early Alzheimer's disease

50 - 85 years of age All Phase N/A
H Hector Cervantes, MS

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

The goal of this clinical trial is to test 6 months of aerobic exercise in older adults who are 65 years or older and have mild cognitive impairment (MCI) or probable/possible mild Alzheimer's Disease. The main questions it aims to answer are: test the effects of aerobic exercise on aerobic …

65 years of age All Phase N/A
S Seung-Hyun Kang

A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284

Primary endpoint of this study is to evaluate the pharmacokinetic characteristics of AD-228B in healthy subjects.

19 years of age All Phase 1
B Binyin Li, Dr

Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease

This study is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in patients with mild cognitive impairment and mild Alzheimer's disease.

60 - 90 years of age All Phase N/A
G Guixian Xiao

High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Early Alzheimer's Disease

To investigate the clinical effect neural mechanism of high-definition transcranial direct current stimulation combined with cognitive training on early AD

50 - 85 years of age All Phase N/A
X Xiaodong Pan

Efficacy and Safety of Transcranial Magnetic Stimulation in Treatment of Alzheimer's Disease

This study is grounded in the regulatory mechanisms of the glymphatic system and applies repetitive transcranial magnetic stimulation (rTMS) to the treatment of Alzheimer's disease (AD). The clinical efficacy and safety of rTMS will be systematically evaluated. Furthermore, transcranial magnetic stimulation-evoked potentials (TMS-EEG) and functional near-infrared spectroscopy (fNIRS) will be …

50 - 90 years of age All Phase N/A
Y Yi Tang, M.D., Ph.D.

Near-infrared Light Therapy Device for Mild-Moderate Alzheimer's Disease (NirsCure-03A)

This study is a multicenter, randomized, double-blind, placebo (sham device)-controlled clinical trial. A total of 320 patients with mild to moderate Alzheimer's disease (AD) are planned to be enrolled. Central stratified block randomization will be applied, with stratification based on disease severity (mild vs. moderate) and PET subgroup participation status …

50 - 85 years of age All Phase 3

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