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Ocular Hypertension Clinical Trials

A listing of Ocular Hypertension medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 103 clinical trials
K Koen Willekens, Prof. Dr.

Low Intraocular Pressure Cataract Surgery With Zeiss Quatera in Glaucoma Patients

You were selected to participate in this observational study because you suffer from glaucoma and cataracts. For the cataract you will have cataract surgery. This study will not affect your treatment, it will only collect data on what is performed before, during and after the procedure. The aim of this …

years of age All Phase N/A

MINIject Global Long-Term Follow-up Study

The study will assess the long-term (up to 5 years) safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.

18 - 99 years of age All Phase N/A
B Brian Shafer, MD

A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients

Background Glaucoma is a progressive optic neuropathy characterized by elevated intraocular pressure (IOP), leading to irreversible vision loss. Current treatment strategies often involve medications, which can be challenging for patients due to adherence issues and side effects. Direct Selective Laser Trabeculoplasty (DSLT) represents a potential surgical alternative for managing IOP …

18 years of age All Phase N/A
J James R Masunaga

24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring

The goal of this clinical trial is to learn if a new contact lens device can record patterns in eye pressure for 24 hours in adults with glaucoma and in healthy participants. The main questions it aims to answer are: Is the contact lens device able to detect patterns in …

22 - 80 years of age All Phase N/A
Y Ygal Rotenstreich, MD

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to short and long wavelength stimuli should be significantly lower compared to healthy participants in areas of visual field defects in retinal dystrophy and Glaucoma patients.

18 - 80 years of age All Phase N/A
X Xinbo Gao, MD, PhD

Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study

The drainage angle in the anterior chamber of the eye mediates the outflow of aqueous humor, and pathological changes here can lead to high intraocular pressure and glaucoma. Minimally invasive glaucoma surgery, particularly angle surgery, has advanced recently, allowing clear visualization of angle structures like the trabecular meshwork and Schlemm's …

30 - 85 years of age All Phase N/A
N Nikoloz Labauri, MD. FVRS

Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) Shunt

The goal of this observational study is to evaluate the long-term safety and efficacy of a modified suprachoroidal silicone tube (SST) shunt in treating patients with primary open-angle glaucoma (POAG) and pseudo-exfoliative glaucoma (PXG). The main questions it aims to answer are: Does the SST shunt maintain intraocular pressure (IOP) …

40 - 90 years of age All Phase N/A
C Cédric LAMIREL

Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma

The glycocalyx is a fibrillary lining structure that covers the inner surface of blood vessels. Composed of glycoproteins and polysaccharides, it is an essential determinant of vascular endothelial physiology: it limits coagulation activation and adapts capillary perfusion. Studies have shown glycocalyx alteration in various vascular and autoimmune pathologies such as …

18 years of age All Phase N/A
I Ingeborg Stalmans, Phd

Vitreopapillary Interface and Optic Disc Morphology

The vitreous fills the posterior chamber of the eye and is firmly attached, at the posterior pole, to the macula and the optic nerve head (ONH). With formation of a stepwise posterior vitreous detachment (PVD) exerted tractional forces could influence retinal functioning. Especially in patients with glaucoma the influence of …

18 years of age All Phase N/A
R Rachel Simpson, MD

Anterior Segment Optical Coherence Tomography Microstent Positioning

The goal of this observational study is to learn about the long-term results of glaucoma stent surgery in men and women 18 or older who have had cataract and microstent surgery in the past 2 years at the Moran Eye Center. The main questions the study aims to answer are: …

18 - 100 years of age All Phase N/A

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